Complement and renal transplantation: from donor to recipient

Transplantation
Jeffrey DammanMarc A Seelen

Abstract

Long-term kidney graft survival is affected by different variables including donor condition, ischemia-reperfusion injury, and graft rejection during the transplantation process. The complement system is an important mediator of renal ischemia-reperfusion injury and in rejecting allografts. However, donor complement C3 seems to be crucial in renal transplantation-related injury as renal injury is attenuated in C3 deficient kidney grafts. Interestingly, before ischemia-reperfusion induced C3 expression, C3 is already induced in donors suffering from brain death. Therefore, strategies targeting complement activation in the brain-dead donor may increase graft viability and transplant outcome.

References

Dec 1, 1991·Clinical and Experimental Immunology·H E FeuchtE Albert
Aug 10, 1995·The New England Journal of Medicine·P I TerasakiS Takemoto
Jun 1, 1993·Kidney International·H E FeuchtE Albert
Feb 15, 1996·The Journal of Clinical Investigation·K J KellyJ V Bonventre
Jun 15, 1996·Transplantation·J D PirschF O Belzer
Mar 1, 1996·Transplant Immunology·J R PrattS H Sacks
Jan 1, 1996·Advances in Immunology·M K LiszewskiJ P Atkinson
May 1, 1997·Kidney International·H RabbH R Brady
Feb 26, 1998·Immunopharmacology·M Kirschfink
Jan 12, 1999·The Journal of Clinical Investigation·H F ZhangS Tomlinson
Sep 16, 1999·The Journal of Clinical Investigation·M A DaemenW A Buurman
May 17, 2000·The Journal of Clinical Investigation·W ZhouS H Sacks
Jun 3, 2000·Annual Review of Immunology·D T Fearon, M C Carroll
Jul 21, 2000·Annals of Surgery·J PratschkeN L Tilney
Apr 5, 2001·The New England Journal of Medicine·M J Walport
Apr 12, 2001·The New England Journal of Medicine·M J Walport
Jan 15, 2002·American Journal of Physiology. Renal Physiology·Pierce ParkRichard J Quigg
Jun 4, 2002·Nature Medicine·Julian R PrattSteven H Sacks
Dec 11, 2002·Kidney International·Thiruma V ArumugamStephen M Taylor
Jan 23, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Joshua M ThurmanV Michael Holers
Mar 21, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Bart de VriesWim A Buurman
Sep 10, 2003·The Journal of Immunology : Official Journal of the American Association of Immunologists·Melissa J Burne-TaneyHamid Rabb
Sep 23, 2003·Current Opinion in Immunology·Steven H SacksWuding Zhou
Oct 21, 2003·Proceedings of the National Academy of Sciences of the United States of America·Anna RichardsTimothy H J Goodship
May 4, 2004·Trends in Molecular Medicine·Timothy H J GoodshipJohn P Atkinson
May 26, 2004·Molecular Immunology·Michael C Carroll
May 29, 2004·Transplantation·Meike SchaubFokko J van der Woude
Aug 4, 2004·Circulation·Vedat DavutogluIlyas Akdemir

❮ Previous
Next ❯

Citations

May 28, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Paolo CravediRoslyn B Mannon
Jul 16, 2010·Current Opinion in Organ Transplantation·Elham AsgariSteven Sacks
Jan 23, 2010·Journal of the American Society of Nephrology : JASN·Aleksey NakorchevskyDaniel R Salomon
Aug 21, 2012·Clinical Journal of the American Society of Nephrology : CJASN·Wojciech BłogowskiTeresa Starzyńska
Jul 3, 2010·Clinical Journal of the American Society of Nephrology : CJASN·Marina NorisGiuseppe Remuzzi
Jul 25, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Azadeh ZaferaniJacob van den Born
Jun 7, 2014·Current Opinion in Organ Transplantation·Julia MenkeJens Lutz
Nov 11, 2014·Fibrogenesis & Tissue Repair·Juan S DanobeitiaLuis A Fernandez
Dec 4, 2010·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jeffrey DammanMarc A Seelen
Oct 29, 2013·Seminars in Nephrology·James W McCulloughJoshua M Thurman
Mar 16, 2013·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Jennifer A McCaughanAisling E Courtney
Sep 26, 2015·Clinical and Experimental Immunology·M A KhanD C Broering
Feb 26, 2010·Kidney International·Iris C Vermeulen WindsantMichael J Jacobs
Nov 16, 2010·The Journal of Surgical Research·Ledia GogaClaudio Maldonado
May 31, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·F CasiraghiM Noris
Mar 23, 2013·Clinical Transplantation·A Nicholas R BarnettNizam Mamode
Dec 18, 2013·Pediatric Transplantation·Michael KaabakTatyana Novozhilova
Oct 25, 2011·The American Journal of Pathology·Jinyan ZhangZhihai Peng
Nov 26, 2015·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M Z AkhtarR J Ploeg
Jun 1, 2017·Molecular Immunology·Neeltina M JagerMarc A Seelen
May 14, 2017·The Journal of Immunology : Official Journal of the American Association of Immunologists·Anjan K BongoniPeter J Cowan
Mar 6, 2018·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Qi ChengCarl Atkinson
Dec 12, 2018·Journal of Leukocyte Biology·Mohammad Afzal Khan, Talal Shamma
Apr 5, 2019·Transplantation·Mel BergerStanley C Jordan
Jul 22, 2017·Transplantation·Felix PoppelaarsJeffrey Damman
May 29, 2014·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Elham AsgariSteven H Sacks
Jan 11, 2020·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Juan S DanobeitiaLuis A Fernandez
Apr 12, 2017·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Felix PoppelaarsMarc A Seelen
Dec 21, 2018·American Journal of Respiratory Cell and Molecular Biology·Kunal J PatelCarl Atkinson
Jan 10, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Mark C HowardSteven H Sacks
Apr 28, 2019·Archivum Immunologiae Et Therapiae Experimentalis·Dorota BartoszekMarian Klinger
Oct 23, 2019·Frontiers in Immunology·Monica Grafals, Joshua M Thurman
Apr 4, 2021·Journal of Clinical Medicine·Carlos Arias-CabralesJulio Pascual
May 18, 2021·American Journal of Physiology. Renal Physiology·Sorena LoNirmala Parajuli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Jeffrey DammanMarc A Seelen
The New England Journal of Medicine
M J Walport
© 2022 Meta ULC. All rights reserved