Complete blood count alterations due to the opioid use: what about the lymphocyte-related ratios, especially in monocyte to lymphocyte ratio and platelet to lymphocyte ratio?

Journal of Immunoassay & Immunochemistry
Mehmet Hamdi OrumAysun Kalenderoglu

Abstract

This study was designed to compare the complete blood count values of opioid users (N = 61) and healthy subjects (N = 61), particularly monocyte-to-lymphocyte ratio (MLR) and platelet-to-lymphocyte ratio (PLR). PLR, MLR, and percentage of monocyte (MONO%) were significantly lower in opioid use disorder (OUD) group (P = 0.012, P = 0.005, P = 0.000). The area under the ROC curve of MLR and PLR levels for OUD was 0.349 and 0.368. MONO% correlated with substance use duration. Measurements like lymphocyte-related ratios and MONO% in opioid use can be important in substance monitoring, detection, and differentiation of acute and chronic conditions.

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Citations

Apr 28, 2020·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Andrea AgugliaGianluca Serafini
Nov 30, 2019·International Journal of Clinical Oncology·Tunyaporn KamonvarapitakHiroshi Yoshida
Jun 27, 2018·Journal of Immunoassay & Immunochemistry·Mehmet Hamdi OrumOguzhan Bekir Egilmez
Dec 18, 2019·Journal of Immunoassay & Immunochemistry·Mehmet Hamdi Orum, Mahmut Zabit Kara
Aug 31, 2021·Frontiers in Psychiatry·Bianca M BryantLi Li

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