Complete cytoreduction combined with early postoperative intraperitoneal chemotherapy for ovarian carcinosarcoma. Report of two cases

Gynecologic and Obstetric Investigation
A XanthoulisAntonios-Apostolos K Tentes

Abstract

The purpose of the study is to report two long-term survivors with ovarian carcinosarcomas, which are rare intrapelvic malignancies with unfavorable prognosis. Two middle-aged women with palpable abdominal tumors underwent complete cytoreductive surgery and no macroscopic tumor was left behind. Early postoperative intraperitoneal chemotherapy with doxorubicin was used as an adjuvant treatment. The patients are disease-free 2 and 3 years, respectively after the initial therapy. Complete cytoreduction combined with early postoperative intraperitoneal chemotherapy seems to be an effective treatment for ovarian carcinosarcoma with peritoneal spread. Further studies are required to define the value of intraperitoneal chemotherapy in ovarian carcinosarcoma.

References

Feb 2, 2000·Langenbeck's Archives of Surgery·P H Sugarbaker
Jun 8, 2002·Gynecologic Oncology·Linda R DuskaArlan F Fuller
May 12, 2004·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·H Müller, V Nakchbandi

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