Complete genome sequence analysis of the Malacosoma neustria nucleopolyhedrovirus from Turkey

Virus Genes
Donus GencerIsmail Demir

Abstract

The lackey moth, Malacosoma neustria (Linnaeus, 1758), a worldwide pest, causes extensive economic losses particularly on hazelnut, plum, oak, poplar, and willow trees. A baculovirus, Malacosoma neustria nucleopolyhedrovirus (ManeNPV-T2), has been isolated from the larvae collected in Turkey and appears to have a potential as a microbial control agent. In this study, we describe the complete genome sequence of ManeNPV-T2 and compare it to other sequenced baculovirus genomes. The ManeNPV-T2 genome is a circular double-stranded DNA molecule of 130,202 bp, has 38.2% G + C, and is predicted to contain 131 putative open reading frames (ORFs) each with a coding capacity of more then 50 amino acids. There are 27 ORFs with unknown function of which 6 are unique to ManeNPV-T2. Eleven homologous regions (hrs) and two bro genes (bro-a and bro-b) were identified in the genome. There are two homologues of chaB and nicotinamide riboside kinase-1 genes, separated from themselves with a few nucleotides. Additionally, ac145, thought to be per os infectivity factor (pif) gene, is also found as two homologues. All 38 core genes are found in the ManeNPV-T2 genome. The phylogenetic tree of ManeNPV-T2 in relation to 50 other baculoviruses whose geno...Continue Reading

References

Apr 1, 1993·Journal of Virology·N E CrookL K Miller
Dec 24, 1998·Nucleic Acids Research·G Benson
Sep 30, 1999·Virology·T HayakawaS Maeda
Nov 5, 1999·Annual Review of Microbiology·A RoulstonP E Branton
Nov 24, 1999·The Journal of General Virology·W F IJkelJ M Vlak
Jul 24, 2002·Nucleic Acids Research·Kazutaka KatohTakashi Miyata
Jul 18, 2003·The Journal of General Virology·Gorben P PijlmanJust M Vlak
Nov 15, 2003·Journal of Invertebrate Pathology·C ReedH L Williams
Nov 30, 2005·Virology·Johannes A JehleRüdiger Hauschild
Aug 9, 2006·The Journal of General Virology·Motoko IkedaMichihiro Kobayashi
Oct 13, 2006·The Journal of General Virology·Juliana Velasco de Castro OliveiraPaolo Marinho de Andrade Zanotto
Jan 16, 2007·Advances in Virus Research·Jeffery Slack, Basil M Arif
Apr 7, 2007·The Journal of General Virology·Sally Hilton, Doreen Winstanley
May 12, 2009·Virus Research·Yue JiangZhihong Hu
Aug 31, 2012·Journal of Virology·Matías Javier GaravagliaPablo Daniel Ghiringhelli
Mar 24, 2016·Molecular Biology and Evolution·Sudhir KumarKoichiro Tamura

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Software Mentioned

MAFFT
BioEdit
illumina
HCS
Tandem Repeats Finder
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RTA
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