Complete Genome Sequence and Comparative Genomics of a Novel Myxobacterium Myxococcus hansupus

PloS One
Gaurav SharmaSrikrishna Subramanian

Abstract

Myxobacteria, a group of Gram-negative aerobes, belong to the class δ-proteobacteria and order Myxococcales. Unlike anaerobic δ-proteobacteria, they exhibit several unusual physiogenomic properties like gliding motility, desiccation-resistant myxospores and large genomes with high coding density. Here we report a 9.5 Mbp complete genome of Myxococcus hansupus that encodes 7,753 proteins. Phylogenomic and genome-genome distance based analysis suggest that Myxococcus hansupus is a novel member of the genus Myxococcus. Comparative genome analysis with other members of the genus Myxococcus was performed to explore their genome diversity. The variation in number of unique proteins observed across different species is suggestive of diversity at the genus level while the overrepresentation of several Pfam families indicates the extent and mode of genome expansion as compared to non-Myxococcales δ-proteobacteria.

References

Oct 5, 1990·Journal of Molecular Biology·S F AltschulD J Lipman
Mar 8, 2002·Current Biology : CB·Charles WolgemuthGeorge Oster
Apr 3, 2002·Journal of Biosciences·Gautam Aggarwal, Ramakrishna Ramaswamy
Feb 5, 2004·Genome Biology·Stefan KurtzSteven L Salzberg
Sep 28, 2005·Current Opinion in Genetics & Development·Duccio MediniRino Rappuoli
Dec 31, 2005·Nucleic Acids Research·Roy R Chaudhuri, Mark J Pallen
Mar 4, 2006·Science·Francesca D CiccarelliPeer Bork
Oct 4, 2006·Proceedings of the National Academy of Sciences of the United States of America·B S GoldmanH B Kaplan
Apr 25, 2007·Nucleic Acids Research·Karin LagesenDavid W Ussery
May 15, 2007·Bioinformatics·Feng Gao, Chun-Ting Zhang
Oct 9, 2007·Nature Reviews. Microbiology·David R ZusmanJohn R Kirby
Oct 30, 2007·Nature Biotechnology·Susanne SchneikerRolf Müller
Feb 2, 2008·BMC Bioinformatics·Feng Gao, Chun-Ting Zhang
Feb 12, 2008·BMC Genomics·Ramy K AzizOlga Zagnitko
Mar 22, 2008·FEMS Microbiology Letters·Mika MiyashitaYasuyoshi Nakagawa
Oct 15, 2008·Genome Biology·Martin Wu, Jonathan A Eisen
Nov 6, 2008·International Journal of Systematic and Evolutionary Microbiology·Elke LangErko Stackebrandt
Jan 27, 2009·Trends in Genetics : TIG·Pascal Lapierre, J Peter Gogarten
Jun 13, 2009·FEMS Microbiology Reviews·James E Berleman, John R Kirby
Jul 7, 2009·Annual Review of Microbiology·Gregory J Velicer, Michiel Vos
Nov 26, 2009·Biology Direct·Margrethe H SerresMonica Riley
May 29, 2010·Microbiology and Molecular Biology Reviews : MMBR·Emilia M F MaurielloDavid R Zusman
Jul 9, 2010·Cold Spring Harbor Perspectives in Biology·Dale KaiserLee Kroos
Oct 22, 2010·BMC Genomics·Marit S BratlieFinn Drabløs
Nov 3, 2010·Molecular Biology and Evolution·Stuart HuntleyLotte Søgaard-Andersen
Apr 8, 2011·Nucleic Acids Research·Ivica Letunic, Peer Bork
Apr 30, 2011·BMC Bioinformatics·Marcus LechnerSonja J Prohaska
Aug 10, 2011·BMC Genomics·Nabil-Fareed AlikhanScott A Beatson
Aug 13, 2011·Physical Biology·Yilin WuMark Alber
Aug 27, 2011·Journal of Bacteriology·Zhi-Feng LiYue-Zhong Li
Sep 14, 2011·Annual Review of Genetics·Beiyan Nan, David R Zusman
Sep 29, 2011·Briefings in Bioinformatics·Juan WangQing-hua Cui
Sep 29, 2011·Briefings in Bioinformatics·Julien Y Dutheil
Nov 1, 2011·PLoS Computational Biology·Sean R Eddy
Sep 15, 2012·Proceedings. Biological Sciences·Fyodor A Kondrashov
Mar 22, 2013·Genome Announcements·Stuart HuntleyLotte Søgaard-Andersen
May 7, 2013·Nature Methods·Chen-Shan ChinJonas Korlach
Jun 22, 2013·Genome Announcements·Susanne MüllerJohn R Kirby
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Nov 30, 2013·Nucleic Acids Research·Robert D FinnMarco Punta
Nov 8, 2014·Nucleic Acids Research·Richard J RobertsDana Macelis

❮ Previous
Next ❯

Citations

Apr 6, 2017·Genome Biology and Evolution·Gaurav Sharma, Srikrishna Subramanian
Oct 28, 2017·Genome Announcements·Anke Treuner-LangeLotte Søgaard-Andersen
Oct 28, 2017·Genome Announcements·Anke Treuner-LangeLotte Søgaard-Andersen
Nov 11, 2017·Genome Announcements·Anke Treuner-LangeLotte Søgaard-Andersen
Nov 22, 2017·Journal of Bacteriology·Gaurav SharmaSrikrishna Subramanian
Jun 10, 2020·PLoS Biology·Salim T IslamEmilia M F Mauriello
Aug 4, 2018·Frontiers in Microbiology·Gaurav SharmaMitchell Singer
Nov 12, 2020·Microorganisms·David E Whitworth, Allison Zwarycz
Jul 29, 2017·Biochemical and Biophysical Research Communications·Sonal MahajanT N C Ramya
Jun 2, 2021·Folia Microbiologica·Akansha Shrivastava, Rakesh Kumar Sharma
Oct 13, 2019·Genomics·Damion L WhitfieldMitchell Singer

❮ Previous
Next ❯

Datasets Mentioned

BETA
CP012109
PRJNA167109
AKQ68170
AKQ68203
PRJNA199464

Methods Mentioned

BETA
Scanning Electron Microscopy
PLAT

Software Mentioned

tRNAscan
xBASE
Quiver
GGDC
SMRT
IGS
IMG
iTOL
mummer
ClustalW

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.