Complete mitochondrial DNA analysis of eastern Eurasian haplogroups rarely found in populations of northern Asia and eastern Europe.

PloS One
Miroslava DerenkoIlia Zakharov

Abstract

With the aim of uncovering all of the most basal variation in the northern Asian mitochondrial DNA (mtDNA) haplogroups, we have analyzed mtDNA control region and coding region sequence variation in 98 Altaian Kazakhs from southern Siberia and 149 Barghuts from Inner Mongolia, China. Both populations exhibit the prevalence of eastern Eurasian lineages accounting for 91.9% in Barghuts and 60.2% in Altaian Kazakhs. The strong affinity of Altaian Kazakhs and populations of northern and central Asia has been revealed, reflecting both influences of central Asian inhabitants and essential genetic interaction with the Altai region indigenous populations. Statistical analyses data demonstrate a close positioning of all Mongolic-speaking populations (Mongolians, Buryats, Khamnigans, Kalmyks as well as Barghuts studied here) and Turkic-speaking Sojots, thus suggesting their origin from a common maternal ancestral gene pool. In order to achieve a thorough coverage of DNA lineages revealed in the northern Asian matrilineal gene pool, we have completely sequenced the mtDNA of 55 samples representing haplogroups R11b, B4, B5, F2, M9, M10, M11, M13, N9a and R9c1, which were pinpointed from a massive collection (over 5000 individuals) of northe...Continue Reading

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Citations

Jan 24, 2013·PloS One·Marta Mielnik-SikorskaTomasz Grzybowski
Oct 18, 2013·Journal of Human Genetics·Boris MalyarchukIlya Zakharov
Oct 11, 2014·BMC Evolutionary Biology·Miroslava DerenkoIlya Zakharov
Mar 20, 2016·Molecular Biology and Evolution·Irina PugachBrigitte Pakendorf
Nov 16, 2012·PloS One·Mercedes González-RuizAssumpció Malgosa
Mar 8, 2017·Scientific Reports·Anna JurasAnders Götherström
Dec 8, 2017·Journal of Human Genetics·Miroslava DerenkoBoris Bazarov
Jan 19, 2018·American Journal of Physical Anthropology·Lukáš ŠebestRadoslav Beňuš
Dec 21, 2019·Annals of Human Biology·Adikarla SyamaUNKNOWN Genographic Consortium
Nov 12, 2016·BMC Evolutionary Biology·Patricia MarreroVicente M Cabrera
Jun 14, 2018·Scientific Reports·Gülşah Merve KılınçAnders Götherström
Aug 21, 2015·PloS One·Antonio González-MartínHéctor Rangel-Villalobos
Apr 24, 2018·American Journal of Physical Anthropology·Jiawei LiHui Zhou
Nov 30, 2019·Forensic Science International. Genetics·Kimberly Sturk-AndreaggiCharla Marshall
Nov 11, 2021·Molecular Genetics and Genomics : MGG·Miroslava DerenkoBoris Bazarov

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Methods Mentioned

BETA
MDS
dissection

Software Mentioned

mtPhyl
STATISTICA
Network
FamilyTreeDNA
PhyloTree
Arlequin

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