Complete nucleotide sequence and genome organization of Grapevine leafroll-associated virus 3, type member of the genus Ampelovirus

The Journal of General Virology
Kai-Shu LingD Gonsalves

Abstract

This study reports on the complete genome sequence of Grapevine leafroll-associated virus 3, the type member of the genus Ampelovirus. The genome is 17 919 nt in size and contains 13 open reading frames (ORFs). Previously, the sequence of 13 154 nt of the 3'-terminal of the genome was reported. The newly sequenced portion contains a 158 nt 5' UTR, a single papain-like protease and a methyltransferase-like (MT) domain. ORF1a encodes a large polypeptide with a molecular mass of 245 kDa. With a predicted +1 frameshift, the large fusion protein generated from ORF1a/1b would produce a 306 kDa polypeptide. Phylogenetic analysis using MT domains further supports the creation of the genus Ampelovirus for mealy-bug-transmitted viruses in the family Closteroviridae.

References

Apr 20, 1995·Virology·A V KarasevR F Lee
Nov 10, 2001·Annual Review of Phytopathology·Alexander V Karasev
Oct 12, 2002·Archives of Virology·G P MartelliUNKNOWN ICTV Study Group on closteroviruses and allied viruses

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Citations

Jun 16, 2006·Functional & Integrative Genomics·C EspinozaP Arce-Johnson
May 24, 2008·Virus Genes·Esteban A EngelPablo D T Valenzuela
Nov 28, 2009·Epidemiology and Infection·A VantarakisY Alamanos
Mar 15, 2006·Virus Research·Valerian V DoljaJari P T Valkonen
Apr 22, 2015·Annual Review of Phytopathology·Dennis Gonsalves
Jan 23, 2019·Plant Disease·Brandon D ThompsonAlexander V Karasev
Nov 3, 2020·AIMS Microbiology·Sergey Y Morozov, Andrey G Solovyev
Dec 20, 2020·Viruses·Yaqin WangXueping Zhou

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