Complete nucleotide sequence of Sesbania mosaic virus: a new virus species of the genus Sobemovirus

Archives of Virology
G L LokeshH S Savithri

Abstract

The complete nucleotide sequence of the Sesbania mosaic virus (SeMV) genomic RNA was determined by sequencing overlapping cDNA clones. The SeMV genome is 4149 nucleotides in length and encodes four potential overlapping open reading frames (ORFs). Comparison of the nucleotide sequence and the deduced amino acid sequence of the four ORFs of SeMV with that of other sobemoviruses revealed that SeMV was closest to southern bean mosaic virus Arkansas isolate (SBMV-Ark, 73% identity). The 5' non-coding regions of SeMV, SBMV and southern cowpea mosaic virus (SCPMV) are nearly identical. However ORF1 of SeMV which encodes for a putative movement protein of M(r) 18370 has only 34% identity with SBMV-Ark. ORF 2 encodes a polyprotein containing the serine protease, genome linked viral protein (VPg) and RNA dependent RNA polymerase domains and shows 78% identity with SBMV-Ark. The N-terminal amino acid sequence of VPg was found to be TLPPELSIIEIP, which mapped to the region 326-337 of ORF2 product and the cleavage site between the protease domain and VPg was identified to be E325-T326. The cleavage site between VPg and RNA dependent RNA polymerase was predicted to be E445-T446 based on the amino acid sequence analysis of the polyprotein fr...Continue Reading

Citations

Nov 23, 2006·Archives of Virology·M Meier, E Truve
Nov 9, 2006·Proceedings of the National Academy of Sciences of the United States of America·Vladimir A Belyi, M Muthukumar
Dec 3, 2010·The FEBS Journal·Soumya Roy Chowdhury, Handanahal Subbarao Savithri
Oct 29, 2009·Virology·Smita Nair, H S Savithri
Jul 11, 2016·Archives of Virology·G P Vishnu VardhanM Hema
Jun 10, 2005·The Journal of Biological Chemistry·Panayampalli Subbian SatheshkumarHandanahal Subbarao Savithri
Sep 19, 2006·Environmental Biosafety Research·Merike Meier, Erkki Truve
Sep 12, 2020·Biomaterials Science·Sourabh ShuklaNicole F Steinmetz
Nov 16, 2018·Archives of Virology·G P Vishnu VardhanM R N Murthy
Feb 6, 2021·Virology·Christian Isalomboto Nkanga, Nicole F Steinmetz
Sep 7, 2017·Journal of Chemical Theory and Computation·Matı As R MachadoSergio Pantano

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