Complete sequence of a bla(KPC)-harboring cointegrate plasmid isolated from Escherichia coli

Antimicrobial Agents and Chemotherapy
Kalyan D ChavdaBarry N Kreiswirth

Abstract

Horizontal transfer of bla(KPC)-harboring plasmids contributes significantly to the inter- and intraspecies spread of Klebsiella pneumoniae carbapenemase (KPC). Here we report the complete nucleotide sequence of a bla(KPC)-harboring IncFIA plasmid, pBK32533, from Escherichia coli. pBK32533 is a cointegrate plasmid comprising of a 72-kb sequence identical to that of the nonconjugative pBK30661 plasmid plus an additional 170-kb element that harbors the genes for plasmid transfer. pBK32533 demonstrates how bla(KPC) can be spread from a nonconjugative plasmid through cointegration.

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Feb 5, 2014·Antimicrobial Agents and Chemotherapy·Liang ChenBarry N Kreiswirth
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Citations

Jul 8, 2017·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Yanping LuoShenghui Cui
Jan 10, 2018·Antimicrobial Agents and Chemotherapy·Stefanie DesmetErik Bathoorn
Apr 27, 2016·Antimicrobial Agents and Chemotherapy·Kalyan D ChavdaBarry N Kreiswirth
Nov 11, 2020·Proceedings of the National Academy of Sciences of the United States of America·Katelyn E Zulauf, James E Kirby
Nov 18, 2020·Microorganisms·Andrey ShelenkovVasiliy Akimkin
Mar 25, 2021·Mobile DNA·Alessandro VaraniMichael Chandler
Apr 20, 2021·Journal of Microbiological Methods·Katja ProbstAlexander H Dalpke
Jul 1, 2021·Clinical Microbiology Reviews·F BaqueroT M Coque

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