Completeness of lymph node dissection in patients undergoing minimally invasive- or open surgery for non-small cell lung cancer: A nationwide study.

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Lisa van der WoudeAd F T M Verhagen

Abstract

In patients with NSCLC, lymph node metastases are an important prognostic factor. Despite an accurate pre-operative work up, for optimal staging an intrapulmonary- and mediastinal lymph node dissection (LND) as part of the operation is mandatory. The aim of this study is to assess the completeness of LND in patients undergoing an intended curative resection for NSCLC in the Netherlands and to compare performance between open surgery and minimally invasive surgery (MIS). The intraoperative LND was evaluated in 7460 patients who had undergone a lobectomy for clinically staged N0-1 NSCLC (2013-2018). The LND was considered complete, when three mediastinal (N2) lymph node stations, including station 7, were sampled or dissected, in addition to the lymph nodes from station 10 and 11. A comparison was made between open surgery and MIS. Of 5154 patients, who had MIS, a sufficient intrapulmonary LND was performed in 47.9% and a sufficient mediastinal LND in 58.6%. A complete LND was performed in 31.6%. For 2306 patients who had an open resection, these numbers were 45.0%, 59.0%, and 30.6%, respectively. The overall between-hospital variation in a complete LND ranged between 0 and 72.5%. In the Netherlands, a complete LND of both intrap...Continue Reading

References

Mar 3, 2005·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jarosław KuzdzałJuliusz Pankowski
Jun 14, 2005·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Ramón Rami-PortaUNKNOWN International Association for the Study of Lung Cancer (IASLC) Staging Committee
Sep 15, 2006·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Didier LardinoisWalter Weder
May 25, 2010·The Annals of Thoracic Surgery·Chadrick E DenlingerTraves Crabtree
Jul 2, 2011·The Annals of Thoracic Surgery·Thomas A D'AmicoMark W Onaitis
May 24, 2012·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Erik M von MeyenfeldtMichel W J M Wouters
Jun 30, 2012·The Annals of Thoracic Surgery·Daniel J BoffaMark Onaitis
Jan 9, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Emanuel PaladeSebastian Wiesemann
Jan 16, 2013·The Thoracic and Cardiovascular Surgeon·Dohun KimYoung Mog Shim
Aug 6, 2013·The Annals of Thoracic Surgery·Raymond U Osarogiagbon, Xinhua Yu
Aug 7, 2013·The Annals of Thoracic Surgery·Robert E MerrittJoseph B Shrager
Oct 3, 2015·The Annals of Thoracic Surgery·Jeremiah T MartinJoseph Zwischenberger
Jan 23, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Rachel L MedberyFelix G Fernandez
Jan 29, 2016·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Herbert DecaluwéUNKNOWN Leuven Lung Cancer Group
Feb 16, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Andrea BilleDavid R Jones
Aug 26, 2017·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Matteo GagliassoFrancesco Ardissone
Jan 27, 2018·The Journal of Thoracic and Cardiovascular Surgery·Sebron HarrisonBrendon Stiles
Apr 25, 2018·The Annals of Thoracic Surgery·Martijn Ten BergeMichel Wilhelmus Wouters
Apr 23, 2019·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Jie DaiPeng Zhang
Nov 16, 2019·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·John G EdwardsUNKNOWN International Association for the Study of Lung Cancer Staging and Prognostic Factors Committee, Advisory Board Members, and
Nov 20, 2019·The Journal of Thoracic and Cardiovascular Surgery·James M ClarkMiriam Nuño
Dec 14, 2019·BJS Open·L R van der WerfH A Prins
Jan 30, 2020·The New England Journal of Medicine·Harry J de KoningMatthijs Oudkerk
Feb 9, 2020·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Federico ReaGiovanni Corrao

❮ Previous
Next ❯

Citations

Jun 12, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Alberto CabañeroGemma Muñoz

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.