Oct 17, 2007

Complex class 1 integrons with diverse variable regions, including aac(6')-Ib-cr, and a novel allele, qnrB10, associated with ISCR1 in clinical enterobacterial isolates from Argentina

Antimicrobial Agents and Chemotherapy
María Paula QuirogaDaniela Centrón

Abstract

Transferable quinolone resistance has not previously been reported in Argentina. Here we describe three complex class 1 integrons harboring the novel allele qnrB10 in a unique region downstream of orf513, one of them also containing aac(6')-Ib-cr within the variable region of integrons. The three arrays differed from bla(CTX-M-2)-bearing integrons, which are broadly distributed in Argentina.

Mentioned in this Paper

Bacterial Proteins
Quinolone Antibacterial Agents
Beta-Lactamase
Integrons
Homologous Sequences, Nucleic Acid
Sequence Determinations, DNA
Alleles
Quinolones
Histocompatibility Antigens Class I
Beta-lactamase CTX-2

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