Abstract
Within a 2-year period in the 1940s, 2 Boston physicians published dramatically opposing views on the underlying nature of a syndrome now known as complex regional pain syndrome (CRPS). Evans suggested, in several papers in 1946-1947, that sympathetic reflexes maintain pain and dystrophy in affected limbs. Foisie, in 1947, suggested arterial vasospasms were key in the etiology of this pain syndrome. Evans' hypothesis established the nomenclature for this syndrome for 60 years, and his term, "reflex sympathetic dystrophy," guided clinical treatment and research activities over the same period. Foisie's proposed nomenclature was unrecognized, and had virtually no impact on the field. Recent evidence suggests that Evans' contribution to the field may have in fact led clinicians and researchers astray all those years. This focus article on CRPS compares recent observations with these 2 earlier theories and asks the question-what if we had adopted Foisie's nomenclature from the beginning? This article discusses 2 opposing historical views on the etiology of what is now known as CRPS, and how they affected nomenclature, research, and clinical therapy in subsequent decades. This focus article may help researchers and clinicians realiz...Continue Reading
Citations
Oct 8, 2013·Chirurgie de la main·A-M GayR Legré
May 31, 2014·Hand Surgery : an International Journal Devoted to Hand and Upper Limb Surgery and Related Research : Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·Hitoshi Hirata
Feb 18, 2015·Anesthesiology Research and Practice·Tracey PonsRoger T Mulder
May 4, 2017·Hand Surgery and Rehabilitation·J LebonP Mansat
Jun 9, 2017·PloS One·Roberta FuscoSalvatore Cuzzocrea
Feb 26, 2016·The Cochrane Database of Systematic Reviews·Keith M SmartNeil E O'Connell
Feb 5, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Eun Jeong ChoYoung Bin Song
Sep 7, 2018·Journal of Cellular and Molecular Medicine·Alexios-Fotios A Mentis, Athanasios G Papavassiliou
Jan 9, 2019·European Journal of Pain : EJP·Andreas GoebelChris Wells
Jun 20, 2014·Pain·Leif OstergaardTroels Staehelin Jensen
Nov 20, 2019·Journal of Neural Transmission·Terence J Coderre, André Laferrière
Dec 20, 2019·Journal of Neurochemistry·Oli A FulasTerence J Coderre
Dec 2, 2020·Pharmaceutics·Oli Abate FulasTerence J Coderre
Oct 6, 2021·ACS Chemical Neuroscience·Oli Abate FulasTerence J Coderre