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Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence Data

Genome Biology and Evolution

Jul 2, 2016

Yaroslav A KainovGeorgii A. Bazykin

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Abstract

Polyadenylation is a step of mRNA processing which is crucial for its expression and stability. The major polyadenylation signal (PAS) represents a nucleotide hexamer that adheres to the AATAAA consensus sequence. Over a half of human genes have multiple cleavage and polyadenylation sit...read more

Mentioned in this Paper

Gene Polymorphism
Species
Polyadenylation Pathway
Genetic Equilibrium
Protein Biosynthesis
Whole Genome Amplification
Single Nucleotide Polymorphism
Genetic Polymorphism
Genetic Translation Process
Patterns
3
18
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Complex Selection on Human Polyadenylation Signals Revealed by Polymorphism and Divergence Data

Genome Biology and Evolution

Jul 2, 2016

Yaroslav A KainovGeorgii A. Bazykin

PMID: 27324920

DOI: 10.1093/gbe/evw137

Abstract

Polyadenylation is a step of mRNA processing which is crucial for its expression and stability. The major polyadenylation signal (PAS) represents a nucleotide hexamer that adheres to the AATAAA consensus sequence. Over a half of human genes have multiple cleavage and polyadenylation sit...read more

Mentioned in this Paper

Gene Polymorphism
Species
Polyadenylation Pathway
Genetic Equilibrium
Protein Biosynthesis
3
18

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  • References52
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