Complex silica composite nanomaterials templated with DNA origami.

Nature
Xiaoguo LiuChunhai Fan

Abstract

Genetically encoded protein scaffolds often serve as templates for the mineralization of biocomposite materials with complex yet highly controlled structural features that span from nanometres to the macroscopic scale1-4. Methods developed to mimic these fabrication capabilities can produce synthetic materials with well defined micro- and macro-sized features, but extending control to the nanoscale remains challenging5,6. DNA nanotechnology can deliver a wide range of customized nanoscale two- and three-dimensional assemblies with controlled sizes and shapes7-11. But although DNA has been used to modulate the morphology of inorganic materials12,13 and DNA nanostructures have served as moulds14,15 and templates16,17, it remains challenging to exploit the potential of DNA nanostructures fully because they require high-ionic-strength solutions to maintain their structure, and this in turn gives rise to surface charging that suppresses the material deposition. Here we report that the Stöber method, widely used for producing silica (silicon dioxide) nanostructures, can be adjusted to overcome this difficulty: when synthesis conditions are such that mineral precursor molecules do not deposit directly but first form clusters, DNA-sili...Continue Reading

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Citations

Nov 7, 2018·Angewandte Chemie·Linh NguyenAmelie Heuer-Jungemann
Jan 22, 2019·Organic & Biomolecular Chemistry·Mashooq AliShou-Jun Xiao
Feb 16, 2019·Advanced Materials·Yong Hu, Christof M Niemeyer
Dec 24, 2018·Chembiochem : a European Journal of Chemical Biology·Fan LiHao Pei
Mar 26, 2019·Small·Fei WangQian Li
Apr 12, 2019·Chemical Communications : Chem Comm·Yanyan YuHuaping Peng
Feb 1, 2019·Chembiochem : a European Journal of Chemical Biology·Bowen ZhuXiaolei Zuo
Apr 25, 2019·Small·Sisi FanJie Song
Jan 17, 2020·Angewandte Chemie·Yueyue ZhangXiaolei Zuo
Feb 12, 2020·Nucleic Acids Research·Antonio SumaVincenzo Carnevale
Mar 5, 2020·Small·Yang XinAdrian Keller
Mar 9, 2020·Topics in Current Chemistry·Xuemei XuYuzhou Wu
Apr 18, 2020·Advanced Materials·Yingxu ShangBaoquan Ding
Apr 19, 2020·Angewandte Chemie·Sisi FanJie Song
Apr 10, 2020·Advanced Materials·Tangi AubertUlrich Wiesner
Sep 25, 2019·Research : a Science Partner Journal·Shaokang RenChunhai Fan
Jul 5, 2019·Nature Protocols·Xinxin JingChunhai Fan
Sep 9, 2020·Nature Chemistry·Guangbao YaoHao Yan
Sep 25, 2020·Nature Communications·Jiajing ZhouFrank Caruso
Mar 10, 2019·Nature Communications·Christian WirajaChenjie Xu
Feb 6, 2020·Topics in Current Chemistry·Yuan ZhaoChuanlai Xu
Apr 8, 2020·Science China. Life Sciences·Fan LiChunhai Fan
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Feb 15, 2020·Chemical Science·Francesca KimKarina Carneiro
Apr 8, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Fanyu MengPeng Miao
Jun 21, 2020·Nature Communications·Ping ZhangChunhai Fan
Mar 16, 2019·Chembiochem : a European Journal of Chemical Biology·Nicholas Stephanopoulos
Apr 1, 2020·Small·Yinan ZhangLihua Wang
Sep 22, 2020·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yueming WuRunhui Liu
Nov 12, 2020·Nature Communications·Lior ShaniOleg Gang
Dec 12, 2020·Chemical Society Reviews·Gezhi KongWeihong Tan

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Methods Mentioned

BETA
transmission
atomic force microscopy
AFM

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