PMID: 16523165Mar 9, 2006Paper

Compliance and persistence

Journal français d'ophtalmologie
M Detry-Morel

Abstract

1) To summarize the literature on compliance (the extent to which the patient's behaviors correspond with the provider's recommendations) and persistence (total time on therapy) in patients with open-angle glaucoma or ocular hypertension. 2) To suggest guidelines to improve these two parameters, which are both essential and integral elements of optimizing patient care. Compliance-related research published between 1980 and March 2005. Medication compliance has mostly been investigated and measured using patient self-reports, electronic monitoring, and medication possession ratio. Noncompliance-related problems are underestimated, complex, unpredictable and frequent. Noncompliance rates of at least 25% have been reported. The main obstacles to medication compliance are situational/environmental or related to the side effects or complexity of the medication regimen. Persistence with glaucoma medications has also been proven to be poor. Based on retrospective studies using survival analyses, fewer than 25% of patients may be persistent over 12 months. Persistence rates differ from one treatment to another and may fluctuate with time in the same patient. Improving the quality of information, the patient-physician relationship, and ...Continue Reading

Citations

Apr 8, 2010·International Ophthalmology·Manuel Marcel HermannMichael Diestelhorst
Apr 5, 2021·Journal of Glaucoma·Neetha I R KuzhuppillySudha Menon

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