Compliance with gastric cancer guidelines is associated with improved outcomes

Journal of the National Comprehensive Cancer Network : JNCCN
David J WorhunskyBrendan C Visser

Abstract

Limited data are available on the implementation and effectiveness of NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Gastric Cancer. We sought to assess rates of compliance with NCCN Guidelines, specifically stage-specific therapy during the initial episode of care, and to determine its impact on outcomes. The California Cancer Registry was used to identify cases of gastric cancer from 2001 to 2006. Logistic regression and Cox proportional hazard models were used to predict guideline compliance and the adjusted hazard ratio for mortality. Patients with TNM staging or summary stage (SS) were also analyzed separately. Compliance with NCCN Guidelines occurred in just 45.5% of patients overall. Patients older than 55 years were less likely to receive guideline-compliant care, and compliance was associated with a median survival of 20 versus 7 months for noncompliant care (P<.001). Compliant care was also associated with a 55% decreased hazard of mortality (P<.001). Further analysis revealed that 50% of patients had complete TNM staging versus an SS, and TNM-staged patients were more likely to receive compliant care (odds ratio, 1.59; P<.001). TNM-staged patients receiving compliant care had a median survival of...Continue Reading

Citations

Aug 8, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Daniela MolenaAnne O Lidor
Mar 30, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Kathryn JaapJoseph Blansfield
Nov 28, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Lei HuangGuo-Xin Li
May 18, 2019·American Society of Clinical Oncology Educational Book·Gabrielle Betty RocquePeter Paul Yu
May 19, 2019·Journal of Surgical Oncology·Mark B UlanjaNageshwara Gullapalli
May 11, 2017·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Majed AlghamdiGerald Lim
Jan 26, 2017·American Journal of Clinical Oncology·Andrew M BlakelyThomas J Miner
Jul 20, 2020·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Anouk E J LatensteinUNKNOWN Dutch Pancreatic Cancer Group
Mar 26, 2021·Annals of Surgical Oncology·Deepa Magge, Marcus Tan
Mar 27, 2021·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Edwin DovigiTrilokraj Tejasvi
Jul 15, 2021·Obstetrics and Gynecology·Victoria E RodriguezRobert E Bristow
Dec 30, 2021·Journal of Surgical Oncology·Gaya SpolveratoTimothy M Pawlik

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