Complications after benign hysterectomy, according to procedure: a population-based prospective cohort study from the Danish hysterectomy database, 2004-2015.

BJOG : an International Journal of Obstetrics and Gynaecology
Annette SettnesHelga Gimbel

Abstract

To compare the risk of complications associated with benign hysterectomy according to surgical procedure. Register-based prospective cohort study. Danish Hysterectomy Database, 2004-2015. All Danish women with benign elective hysterectomy (n = 51 141). Multivariate log-binomial regression to compute relative risks (RRs) stratified by calendar period, and adjusted for age, height, weight, smoking habits, use of alcohol, comorbidity, indications, uterine weight and adhesions. Multiple imputation and 'intention to treat' analyses were performed. Major (grades III-V) and minor (grades I-II) Clavien-Dindo modified complications within 30 days. Overall, major complications occurred in 3577 (7.0%) hysterectomies and minor complications occurred in 4788 (9.4%). The proportions of major and minor complications according to type of hysterectomy were: 10.3 and 9.6% for abdominal hysterectomy (AH); 4.1 and 12.1% for laparoscopic hysterectomy (LH); and 4.9 and 8.0% for vaginal hysterectomy (VH) for non-prolapse, and 2.3 and 6.4% for prolapse. In multivariate analyses, compared with VH for non-prolapse, the risk of major complications was higher for AH (RR 1.82, 95% CI 1.63-2.03) but lower for both LH (RR 0.78, 95% CI 0.68-0.90) and VH for p...Continue Reading

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Citations

Apr 9, 2021·Obstetrics and Gynecology·Melissa P McHaleStephanie L Wethington
Jul 9, 2021·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S KapurubandaraJ Baekelandt

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