Complications after Perforated versus Nonperforated Acellular Dermal Matrix Use in Direct-to-Implant Breast Reconstruction: A Propensity Score Analysis

Plastic and Reconstructive Surgery. Global Open
Kasey Leigh WoodC Andrew Salzberg

Abstract

Acellular dermal matrices (ADMs) were first incorporated into direct-to-implant (DTI) breast reconstruction by the senior author in 2001 and have since become foundational to implant-based reconstruction. ADM composition has evolved recently and now includes perforated types, which some speculate decrease the likelihood of seroma. The authors performed a retrospective review of perforated (P-ADM) and nonperforated (NP-ADM) ADM-assisted direct-to-implant breast reconstruction patients to evaluate differences in complication rates. Retrospective review of direct-to-implant breast reconstruction patients operated on by a single surgeon (CAS) from 2011 to 2018 was conducted. Patient and operative characteristics, including ADM type, were recorded. A propensity score matching algorithm accounting for potentially confounding variables was developed, followed by univariate analysis to evaluate the association between ADM perforation and postoperative complications. The review began with 409 patients (761 breasts). Following exclusion of patients with missing demographic information, lack of ADM in their reconstruction, and follow-up times of less than 4 weeks, 364 patients (680 breasts) were included for analysis. A total of 530 (77.9...Continue Reading

References

Apr 1, 1984·Plastic and Reconstructive Surgery·L A StevensK A Forde
Jun 1, 1995·Burns : Journal of the International Society for Burn Injuries·D J Wainwright
Mar 26, 1998·Plastic and Reconstructive Surgery·A KhooM A Schusterman
Nov 25, 1998·Annals of Plastic Surgery·B M AchauerD G Jacobson
Jun 28, 2002·Plastic and Reconstructive Surgery·Albert LoskenMark Schoemann
Jan 28, 2004·Annals of Plastic Surgery·Brian Buinewicz, Brent Rosen
Jul 17, 2007·Plastic and Reconstructive Surgery·Richard J Zienowicz, Ercan Karacaoglu
Aug 28, 2007·Annals of Plastic Surgery·Karl H Breuing, Amy S Colwell
Mar 14, 2008·Aesthetic Plastic Surgery·S L SpearN G Menon
Jul 3, 2008·Plastic and Reconstructive Surgery·Scott L SpearAli Al-Attar
May 19, 2011·Annals of Plastic Surgery·Catherine de BlacamBernard T Lee
Feb 14, 2012·Plastic and Reconstructive Surgery·Scot B Glasberg, David Light
Nov 1, 2012·Plastic and Reconstructive Surgery·C Andrew Salzberg
Jul 3, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Benny K H Tan
Oct 15, 2013·Statistics in Medicine·Peter C Austin
Oct 28, 2014·Plastic and Reconstructive Surgery·Jenna B MartinGarrett A Wirth
May 15, 2015·Plastic and Reconstructive Surgery. Global Open·Ahmed M S IbrahimSamuel J Lin
Jun 20, 2015·Plastic and Reconstructive Surgery·Donald S MowldsGarrett A Wirth
Oct 7, 2015·Annals of Surgical Oncology·Kyeong-Tae Lee, Goo-Hyun Mun
Feb 20, 2016·Plastic and Reconstructive Surgery. Global Open·David A PalaiaMichael H Rosenberg
Mar 29, 2016·Plastic and Reconstructive Surgery·Sumanas W JordanJohn Y S Kim
May 25, 2016·Plastic and Reconstructive Surgery·Emily M Clarke-PearsonAmy S Colwell
Oct 25, 2017·Plastic and Reconstructive Surgery·John Y S Kim, Alexei S Mlodinow
Jun 8, 2018·Plastic and Reconstructive Surgery. Global Open·Keyianoosh Z PaydarDonald S Mowlds

❮ Previous
Next ❯

Software Mentioned

pwr
R
SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.