Complications of abdominal exploration and splenectomy in staging children with Hodgkin's disease.

Journal of Pediatric Surgery
E R WayneE I Hatch

Abstract

Until alternate diagnostic methods are discovered, the staging procedure seems to be the most reliable method to establish the presence or absence of abdominal involvement in Hodgkin's disease. Our experience with staging laparotomy in 22 children raises serious questions as to both the risk of operation and the prognostic value of a negative abdominal exploration. Routine use of the staging laparotomy may not be justified in clinical Stage IA patients with lymphocyte-predominant cell type. Because of the hazards and limitations of the staging procedure, vigorous attempts would seem to be indicated to identify subcategories of patients in whom the likelihood of intraabdominal involvement is so small as to negate the value of surgical staging.

References

Jan 16, 1971·Lancet·J M Goldman
Apr 26, 1973·The New England Journal of Medicine·A C Aisenberg
Jul 1, 1972·Annals of Internal Medicine·D W Nixon, A C Aisenberg
Sep 1, 1972·British Journal of Haematology·S A Rosenberg
Mar 1, 1974·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·J G RosenstockW B Kiesewetter
Jul 13, 1972·The New England Journal of Medicine·S S DonaldsonK L Vosti
Oct 1, 1972·Journal of Pediatric Surgery·D M HaysM R Karon
Sep 1, 1971·Annals of Internal Medicine·R E Johnson
Jan 1, 1983·Cancer Investigation·T J Kinsella, E Glatstein

❮ Previous
Next ❯

Citations

Nov 30, 1978·The New England Journal of Medicine·G O Strauch
Jan 24, 1980·The New England Journal of Medicine·M O DaileyH S Kaplan
Jan 1, 1980·World Journal of Surgery·P R Exelby
Jan 1, 1983·Cancer Investigation·F Rosner, M H Zarrabi
Mar 1, 1982·The British Journal of Radiology·M D CohenA Siddiqui
Oct 14, 2010·Journal of Neuro-oncology·Daniel M S RaperLinda D Lewis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.