Complications of living donor hepatic lobectomy--a comprehensive report.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
M M AbecassisA2ALL Study Group

Abstract

A wider application of living donor liver transplantation is limited by donor morbidity concerns. An observational cohort of 760 living donors accepted for surgery and enrolled in the Adult-to-Adult Living Donor Liver Transplantation cohort study provides a comprehensive assessment of incidence, severity and natural history of living liver donation (LLD) complications. Donor morbidity (assessed by 29 specific complications), predictors, time from donation to complications and time from complication onset to resolution were measured outcomes over a 12-year period. Out of the 760 donor procedures, 20 were aborted and 740 were completed. Forty percent of donors had complications (557 complications among 296 donors), mostly Clavien grades 1 and 2. Most severe counted by complication category; grade 1 (minor, n = 232); grade 2 (possibly life-threatening, n = 269); grade 3 (residual disability, n = 5) and grade 4 (leading to death, n = 3). Hernias (7%) and psychological complications (3%) occurred >1 year postdonation. Complications risk increased with transfusion requirement, intraoperative hypotension and predonation serum bilirubin, but did not decline with the increased center experience with LLD. The probability of complication ...Continue Reading

References

Mar 15, 2003·Digestive Surgery·Elie Yahchouchy-ChouillardAbe Fingerhut
Jun 15, 2007·Transplantation·James F TrotterUNKNOWN A2ALL Study Group
May 29, 2008·Gastroenterology·Rafik M GhobrialUNKNOWN A2ALL Study Group
Jul 7, 2009·Journal of Hepatology·James W MarshThomas E Starzl
Oct 6, 2009·Gastroenterology·Chris FreiseUNKNOWN A2ALL Study Group
Feb 4, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M GubaI D McGilvray
Mar 11, 2010·Transplantation·Taku IidaShinji Uemoto
Apr 27, 2010·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·L AdcockG Therapondos

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Citations

Feb 8, 2013·Transplantation·Amy D WatermanMatthew Cooper
Nov 28, 2013·World Journal of Gastroenterology : WJG·Maurizio PompiliAlfonso Wolfango Avolio
Jul 16, 2014·Clinics in Liver Disease·James F Trotter
Dec 3, 2014·Clinics in Liver Disease·Laura M Kulik, Attasit Chokechanachaisakul
Apr 22, 2014·Transplantation Reviews·Sohaib Khalid HashmiAbraham Shaked
Nov 26, 2015·Journal of Hepatology·UNKNOWN European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu
Nov 12, 2013·Asian Journal of Surgery·See Ching ChanChung Mau Lo
Sep 4, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Vanessa R HumphrevilleSrinath Chinnakotla
Nov 21, 2013·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Michele MolinariValerie Keough
Sep 13, 2014·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Nir LubezkyMarcelo Facciuto
Feb 21, 2016·Radiologic Clinics of North America·Kristine S BurkDushyant Sahani
Apr 23, 2013·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·Parsia A VagefiChris E Freise
Jan 21, 2016·Journal of Transplantation·Helry L CandidoJoao Seda Neto
Aug 22, 2015·Transplantation Proceedings·H KimuraN Ozaki
Oct 10, 2015·Journal of Hepato-biliary-pancreatic Sciences·Jeong-Ik ParkSung-Gyu Lee
Oct 31, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J F Trotter
Apr 5, 2013·Transplant International : Official Journal of the European Society for Organ Transplantation·Sang Bin HanJae Won Joh
Mar 1, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Garrett R RollJohn Paul Roberts
May 23, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Ryan P CauleyHeung Bae Kim
Jul 20, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·O SoubraneO Scatton
May 19, 2012·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·E J Gordon
Sep 17, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·B SamsteinJ C Emond
Apr 27, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Daniela P Ladner, Talia Baker
Apr 21, 2016·The Medical Clinics of North America·Dianne LaPointe Rudow, Karen M Warburton
Sep 4, 2012·Transplant International : Official Journal of the European Society for Organ Transplantation·Cristiano QuintiniCharles Miller
Mar 19, 2016·Hepatology International·Viniyendra PamechaShiv Kumar Sarin
Dec 10, 2014·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Kyung-Suk SuhKwang-Woong Lee
May 16, 2014·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Robert S BrownDaniela P Ladner
Dec 21, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·O ShakedK R Reddy
Apr 10, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Paul MartinMichael Fallon
Apr 10, 2014·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·D S Goldberg, P L Abt
Dec 10, 2014·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Jean C EmondRobert M Merion
Nov 26, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·F RotellarI Herrero
Jul 22, 2014·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·David S GoldbergAbraham Shaked
Dec 7, 2013·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·G R Roll, J P Roberts
Nov 19, 2013·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Yusuf GunayYaman Tokat
May 21, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Elisa J GordonTalia Baker
May 16, 2015·Psychosomatics·Brian M IacovielloDianne LaPointe Rudow
Aug 22, 2015·Journal of Clinical Psychology in Medical Settings·Dianne LaPointe RudowJennifer L Steel
May 25, 2015·Journal of Hepatology·Elisa J GordonTalia Baker
Apr 8, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Neehar D ParikhMariel Lavieri
Mar 18, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Andrea F DiMartiniBrenda W Gillespie
Mar 20, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Benjamin SamsteinJean Emond
Jan 21, 2015·Transplant International : Official Journal of the European Society for Organ Transplantation·A Claire den DulkBart van Hoek

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