Complications of seasonal and pandemic influenza

Critical Care Medicine
Michael B Rothberg, Sarah D Haessler

Abstract

Influenza is a seasonal viral infection associated with significant morbidity and mortality. In 2009, a novel H1N1 influenza A virus emerged and has been classified as a pandemic. In contrast to seasonal influenza, severe disease from pandemic H1N1 seems concentrated in older children and young adults, with almost no cases reported in patients older than 60 yrs. Although patients with underlying cardiopulmonary disease remain at risk, most complications have occurred among previously healthy individuals, with obesity and respiratory disease as the strongest risk factors. Pulmonary complications are common. Primary influenza pneumonia occurs most commonly in adults and may progress rapidly to acute lung injury requiring mechanical ventilation. Secondary bacterial infection is more common in children. Staphylococcus aureus, including methicillin-resistant strains, is an important cause of secondary bacterial pneumonia with a high mortality rate. Treatment of pneumonia should include empirical coverage for this pathogen. Neuromuscular and cardiac complications are unusual but may occur.

Associated Clinical Trials

References

Oct 1, 1992·The Journal of Infectious Diseases·H ScheiblauerR Rott
Nov 1, 1990·The Journal of Infection·W FoulkesC Sewry
May 1, 1989·Chest·G C Prechter, A K Gerhard
Jun 1, 1971·Archives of Internal Medicine·S W SchwarzmannW M Marine
Jan 15, 1966·British Medical Journal·C H Stuart-Harris
Jan 1, 1983·Journal of Clinical Microbiology·E D RennerC H Tseng
May 13, 1995·BMJ : British Medical Journal·S L JohnstonD A Tyrrell
Oct 16, 1993·BMJ : British Medical Journal·K G NicholsonD C Ireland
May 1, 1996·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E WhimbeyG P Bodey
Sep 17, 1998·Archives of Internal Medicine·K L NicholT von Sternberg
Dec 16, 1998·American Journal of Epidemiology·K M NeuzilM R Griffin
Jan 14, 1999·The New England Journal of Medicine·R Ross
Mar 17, 1999·JAMA : the Journal of the American Medical Association·K M NeuzilM R Griffin
Jan 29, 2000·The New England Journal of Medicine·H S IzurietaK Fukuda
Feb 7, 2001·Journal of Medical Microbiology·N Miyashita, T Matsushima
Sep 15, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·H M RadwanR T Ellison III
Feb 15, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J H RexJ E Edwards
May 22, 2001·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A D FineK Fukuda
Jun 26, 2001·Journal of Medical Virology·L KaiserF G Hayden
Sep 21, 2001·International Journal of STD & AIDS·D J SkiestJ Luby
May 2, 2002·Journal of the American Geriatrics Society·Susan K BowlesUNKNOWN Oseltamivir Compassionate Use Program Group
Jul 5, 2002·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Regis A VilchezShimon Kusne
Aug 13, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tsuneo MorishimaUNKNOWN Collaborative Study Group on Influenza-Associated Encephalopathy in Japan
Dec 21, 2002·The Journal of Antimicrobial Chemotherapy·F Y AokiUNKNOWN IMPACT Study Group
Jan 9, 2003·JAMA : the Journal of the American Medical Association·William W ThompsonKeiji Fukuda
Jul 30, 2003·Archives of Internal Medicine·Laurent KaiserFrederick Hayden
Jan 1, 1959·The Journal of Clinical Investigation·D B LOURIAD E ROGERS
Oct 3, 2003·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·M Studahl
Sep 16, 2004·JAMA : the Journal of the American Medical Association·William W ThompsonKeiji Fukuda
Jan 26, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael G IsonFrederick G Hayden
May 18, 2005·The Journal of Infectious Diseases·Jared A SilvermanJeff Alder
Aug 23, 2005·Proceedings of the American Thoracic Society·Jadwiga A Wedzicha
Sep 30, 2005·The New England Journal of Medicine·John H BeigelUNKNOWN Writing Committee of the World Health Organization (WHO) Consultation on Human Influenza A/H5
May 19, 2006·Emerging Infectious Diseases·Jeffrey C HagemanL Clifford McDonald
Jun 28, 2006·Annals of Internal Medicine·Isaac Starr

❮ Previous
Next ❯

Citations

Jun 8, 2011·Immunology and Cell Biology·Garry W LynchJohn S Sullivan
Dec 8, 2011·The Journal of Infectious Diseases·Kevin B O'BrienStacey Schultz-Cherry
Nov 11, 2011·Clinical and Vaccine Immunology : CVI·Ana VujanicPhilip Sutton
Jan 20, 2012·Clinical and Vaccine Immunology : CVI·Yi-Chun LaiKuo-Chin Huang
Mar 6, 2010·American Journal of Respiratory and Critical Care Medicine·Elisa EstenssoroUNKNOWN Registry of the Argentinian Society of Intensive Care SATI
Nov 15, 2011·Italian Journal of Pediatrics·Valeria TrivellinLuigi Nespoli
May 13, 2010·Critical Care : the Official Journal of the Critical Care Forum·Koenraad F van der SluijsMarcus J Schultz
Dec 3, 2010·Emerging Infectious Diseases·Rhonda Y KroppRachel Rodin
May 3, 2014·International Journal of Molecular Medicine·Parvaneh MehrbodAini Ideris
Mar 22, 2014·Japanese Journal of Infectious Diseases·Yuji FujikuraAkihiko Kawana
Nov 24, 2011·Case Reports in Medicine·Silvio A Namendys-SilvaAngel Herrera-Gómez
Oct 12, 2012·Journal of Global Infectious Diseases·Ketan K PatelSudhir V Shah
Feb 5, 2014·Immunotherapy·Delphine Zbinden, Oriol Manuel
Feb 11, 2011·Current Infectious Disease Reports·Guillermo Domínguez-CheritJose Angel Cordova-Villalobos
Dec 12, 2012·Evidence-based Complementary and Alternative Medicine : ECAM·Hui-Juan CaoHiroshi Kurihara
May 19, 2012·BMJ Case Reports·Alexandra VasconcelosManuela Correia
Nov 27, 2010·European Journal of Pediatrics·Dinçer YildizdaşErgin Ciftçi
Oct 16, 2012·European Journal of Pediatrics·Toru Watanabe
Sep 14, 2012·Expert Review of Respiratory Medicine·David Paul MooreShabir Ahmed Madhi
Apr 17, 2012·Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists·Jyoti BuradSinna Kiruchennan
Apr 11, 2012·Emergency Medicine Clinics of North America·Karen G H Woolfrey
Mar 13, 2012·Hormones and Behavior·Dionne P Robinson, Sabra L Klein
Jun 10, 2011·The Canadian Journal of Cardiology·Kanwal KumarDarren H Freed
Mar 18, 2011·Heart & Lung : the Journal of Critical Care·Rami N KhouzamRichard Schwartz
Mar 15, 2011·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·M Vilà de MugaC Luaces Cubells
Sep 21, 2010·Microbes and Infection·Jin Leng, Daniel R Goldstein
Jun 18, 2010·Vaccine·Marc P GirardMarie Paule Kieny

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Antivirals

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Antivirals (ASM)

Antivirals are medications that are used specifically for treating viral infections. Discover the latest research on antivirals here.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Related Papers

The New England Journal of Medicine
Seema Jain2009 Pandemic Influenza A (H1N1) Virus Hospitalizations Investigation Team
The New England Journal of Medicine
Fatimah S DawoodTimothy M Uyeki
JAMA : the Journal of the American Medical Association
Janice LouieCalifornia Pandemic (H1N1) Working Group
Lancet
Denise J JamiesonNovel Influenza A (H1N1) Pregnancy Working Group
JAMA : the Journal of the American Medical Association
Anand KumarCanadian Critical Care Trials Group H1N1 Collaborative
© 2022 Meta ULC. All rights reserved