Complications of transrectal ultrasound-guided 12-core prostate biopsy: a single center experience with 2049 patients

Turkish Journal of Urology
Ozan EfesoyErdem Akbay

Abstract

Currently, transrectal ultrasound-guided (TRUS) systematic prostate biopsy is the standard procedure in the diagnosis of prostate cancer. Although TRUS-guided prostate biopsy is a safe method, it is an invasive procedure that is not free from complications. In this prospective study we evaluated the complications of a TRUS-guided 12-core prostate biopsy. The study included 2049 patients undergoing transrectal ultrasound-guided 12-core prostate biopsy used in the diagnosis of prostate cancer. The indications for the prostate biopsy were abnormal digital rectal examination findings and/or an elevated serum total prostate specific antigen (PSA) level (greater than 4 ng/mL). The participants received prophylactic oral ciprofloxacin (500 mg) the night before and the morning of the biopsy, followed by 500 mg orally twice daily for 2 days. To prevent development of voiding disorders, the patients also received oral alpha blockers for 30 days starting the day before the procedure. A Fleet enema was self-administered the night before the procedure for rectal cleansing. The complications were assessed both 10 days and 1 month after the biopsy. The mean age, serum total PSA level and prostate volume of the patients were 65.4±9.6 years, 18...Continue Reading

Citations

Jan 4, 2020·Abdominal Radiology·Chandan J DasSadhna Verma
Oct 1, 2020·Cancer Cytopathology·Andrew GayaDadasaheb Akolkar

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