Complications of Treatments for Pediatric Rheumatic Diseases

Pediatric Clinics of North America
Gloria C Higgins

Abstract

Medications to treat children with rheumatic disease include disease-modifying antirheumatic drugs, glucocorticosteroids, and biologic response modifiers that target mediators and cells involved in autoimmunity and inflammation. Although usually well-tolerated, such medications have many possible side effects, of which primary care and emergency providers should be aware. Both disease and immunosuppression contribute to susceptibility to unusual and opportunistic infections, in addition to usual childhood infections for which these children should receive all applicable nonlive vaccines. Close coordination between the rheumatologist and other medical care providers is essential, because medication side effects, infections, and disease flares are difficult to distinguish, and may occur together.

Citations

Oct 3, 2018·Rheumatology International·Ezgi Deniz Batu
Aug 31, 2019·The Orthopedic Clinics of North America·Karen M Bovid, Mary D Moore
Jun 9, 2020·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Cheng-Tsung YangLi-Chieh Wang
Jun 9, 2021·Pediatric Rheumatology Online Journal·Rachel A BrownShoghik Akoghlanian

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