PMID: 4018965Jan 1, 1985Paper

Complications with antibiotics used prophylactically in joint replacement surgery: a case report of cephradine-induced pseudomembranous colitis

International Orthopaedics
A P Roberts, A W Hughes

Abstract

A woman underwent joint replacement surgery with prophylactic antibiotic cover, and subsequently died as a result of pseudomembranous colitis. We have noted a high incidence of antibiotic diarrhoea with cephradine, and suggest that if administration of prophylactic antibiotics is restricted to 3 days or less, the incidence of diarrhoea would diminish, and the therapeutic value of the antibiotics would be maintained.

References

Jul 1, 1976·The British Journal of Surgery·M R KeighleyJ Alexander-Williams
Dec 6, 1975·British Medical Journal·L P GARROD
Nov 1, 1975·British Medical Journal
Jan 1, 1981·The Journal of Bone and Joint Surgery. British Volume·M H WicksM R Hone

Citations

Aug 1, 1995·Journal of Clinical Anesthesia·E Y ChengC R Hennen
Oct 30, 1986·The New England Journal of Medicine·A B Kaiser
Oct 12, 2013·Annals of the Royal College of Surgeons of England·R S AujlaG J Taylor

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