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Components of the lectin pathway of complement activation in paediatric patients of intensive care units

Immunobiology

Feb 7, 2016

A S SwierzkoMaciej Cedzynski

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Abstract

Infections are a major cause of childhood mortality. We investigated components of the lectin pathway of complement activation in the context of sepsis at both genetic and protein levels in neonates, infants and older children. Major components of the lectin pathway and two genes for To...read more

Mentioned in this Paper

Septicemia
Biochemical Pathway
TLR4 gene
MASP2 gene
Systemic Inflammatory Response Syndrome
Mannose Binding Lectin
Genes
Toll-like receptor 4
FCN3 gene
Isolectins
3
1
28
Paper Details
References
  • References50
  • Citations5
12345
  • References50
  • Citations5
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Molecular Bacteriology (ASM)

Molecular bacteriology involves fundamental, translational and application-oriented research on the very diverse roles of bacteria in human health and disease. Discover the latest on molecular bacteriology here.

Molecular Bacteriology

Molecular bacteriology involves fundamental, translational and application-oriented research on the very diverse roles of bacteria in human health and disease. Discover the latest on molecular bacteriology here.

Complement Pathway: Mannose-Binding Lectin

The Mannose-Binding Lectin Complement Pathway is activated when mannose-binding lectin binds to mannose found on the surface of pathogens. Subsequent complement activation is similar to the classical complement pathway, but without the need for antigen-antibody complexes. Discover the latest research here.

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Components of the lectin pathway of complement activation in paediatric patients of intensive care units

Immunobiology

Feb 7, 2016

A S SwierzkoMaciej Cedzynski

PMID: 26850322

DOI: 10.1016/j.imbio.2016.01.003

Abstract

Infections are a major cause of childhood mortality. We investigated components of the lectin pathway of complement activation in the context of sepsis at both genetic and protein levels in neonates, infants and older children. Major components of the lectin pathway and two genes for To...read more

Mentioned in this Paper

Septicemia
Biochemical Pathway
TLR4 gene
MASP2 gene
Systemic Inflammatory Response Syndrome
Mannose Binding Lectin
Genes
Toll-like receptor 4
FCN3 gene
Isolectins
3
1
28

Feeds With Similar Papers

Molecular Bacteriology (ASM)

Molecular bacteriology involves fundamental, translational and application-oriented research on the very diverse roles of bacteria in human health and disease. Discover the latest on molecular bacteriology here.

Molecular Bacteriology

Molecular bacteriology involves fundamental, translational and application-oriented research on the very diverse roles of bacteria in human health and disease. Discover the latest on molecular bacteriology here.

Related Papers

Clinical and Experimental Immunology

Low ficolin-2 levels in common variable immunodeficiency patients with bronchiectasis

Clinical and Experimental ImmunologySeptember 25, 2014
M-L MetzgerU Salzer
Paper Details
References
  • References50
  • Citations5
12345
  • References50
  • Citations5
1

Download from

Publisher
PubMed
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