Composition and roles of intestinal microbiota in children

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Alfredo GuarinoVittoria Buccigrossi

Abstract

To provide an update of the advantages of new-generation molecular diagnostics to study the diversity of intestinal microflora and to evaluate its alteration in human diseases. We review recent advances in understanding the complex ecosystem of gut microbiota based on a dynamic and mutual interaction with the host. In vaginal delivery, the contact with the mother's vaginal and intestinal flora is an important source of Lactobacillus, Prevotella and other Bifidobacterium. On the opposite, in cesarean delivery, direct contact of the mouth of the newborn with vaginal and intestinal microbiota is replaced by exogenous non-maternally derived bacteria colonizing the infants' intestine producing a less diverse flora. The original microbiome settings evolve during the growth converging to three main clusters defined "enterotypes" in the adult age. The key role in human health could depend on the balance between beneficial and harmful microbial species populating the gut, therefore the intestinal microflora can been considered as a potential biomarker and/or therapeutic target in intestinal and extra-intestinal diseases.

References

May 8, 1999·The American Journal of Clinical Nutrition·R I MackieH R Gaskins
Jan 30, 2004·The Journal of Nutrition·Volker Mai, J Glenn Morris
Jul 24, 2004·Molecular and Cellular Probes·Rong-Fu WangCarl E Cerniglia
Apr 23, 2005·Science·Susannah Green TringeEdward M Rubin
Jun 1, 2005·Trends in Biotechnology·Don CowanPia Wittwer
Jul 5, 2006·EMBO Reports·Ann M O'Hara, Fergus Shanahan
Mar 16, 2007·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Eugenia BruzzeseAlfredo Guarino
Jun 28, 2007·PLoS Biology·Chana PalmerPatrick O Brown
May 1, 2009·Nature Reviews. Gastroenterology & Hepatology·Sang H RheeEmeran A Mayer
Aug 19, 2009·Journal of Microbiological Methods·Laurent RoudièreEstelle Jumas-Bilak
Sep 29, 2009·The Journal of Pediatrics·Maka MshvildadzeVolker Mai
Apr 20, 2010·The Journal of Pediatrics·Andreas SchwiertzHenrik Köhler
Jun 23, 2010·BMC Microbiology·Serena SchippaMaria Pia Conte
Aug 4, 2010·Proceedings of the National Academy of Sciences of the United States of America·Carlotta De FilippoPaolo Lionetti
Oct 6, 2010·The British Journal of Nutrition·Marcel RoberfroidAgnes Meheust
Nov 26, 2010·Current Opinion in Gastroenterology·Alfredo Guarino, Antonietta Giannattasio
Dec 15, 2010·Journal of Pediatric Gastroenterology and Nutrition·Raakel LuotoErika Isolauri
Apr 2, 2011·Journal of Perinatology : Official Journal of the California Perinatal Association·R Murgas Torrazza, J Neu
Apr 22, 2011·Nature·Manimozhiyan ArumugamPeer Bork
Jun 2, 2011·Pediatric Research·Caroline L J KarlssonSiv Ahrné
Jul 12, 2011·Gastroenterology·Delphine M SaulnierJames Versalovic
Sep 3, 2011·Science·Gary D WuJames D Lewis
Dec 20, 2011·Digestive Diseases·Davide FestiAntonio Colecchia

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Citations

Jan 11, 2013·The British Journal of Nutrition·Jorge R MujicoAscensión Marcos
Dec 1, 2012·Current Opinion in Gastroenterology·Vittoria BuccigrossiAlfredo Guarino
Nov 28, 2012·Antimicrobial Resistance and Infection Control·Jean Carlet
Jun 25, 2014·Trends in Molecular Medicine·Yuliya E BorreJohn F Cryan
Dec 15, 2015·Birth Defects Research. Part C, Embryo Today : Reviews·Sharon B Meropol, Amy Edwards
Jul 10, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Kai König, Katelyn J Guy
Apr 18, 2015·Frontiers in Physiology·Andrea G BraundmeierBryan A White
Jan 8, 2015·European Journal of Pediatrics·Luc Biedermann, Gerhard Rogler
Nov 18, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Fermín García-Muñoz RodrigoFernando Rodríguez Ramón
Feb 3, 2018·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Nazima Pathan
Jan 1, 2013·Clinical Medicine Insights. Gastroenterology·Asit Ranjan Ghosh
Sep 26, 2014·World Journal of Clinical Pediatrics·Xiao-Zhong HuangJing Lin
Oct 8, 2017·International Journal of Dermatology·Maja Šikić PogačarDušanka Mičetić-Turk
Nov 22, 2017·Brazilian Dental Journal·Priscila Vitor Alves FerreiraSilvana Soléo Ferreira Dos Santos
Dec 27, 2016·Frontiers in Immunology·Anje A Te VeldeIrma Joosten
Oct 28, 2020·Journal of Paediatrics and Child Health·Md Ridwan IslamTahmeed Ahmed
Mar 13, 2015·Journal of Proteome Research·Irene MessanaMassimo Castagnola

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