Composition or Context: Using Transportability to Understand Drivers of Site Differences in a Large-scale Housing Experiment

Epidemiology
Kara E RudolphTheresa L Osypuk

Abstract

The Moving To Opportunity (MTO) experiment manipulated neighborhood context by randomly assigning housing vouchers to volunteers living in public housing to use to move to lower poverty neighborhoods in five US cities. This random assignment overcomes confounding limitations that challenge other neighborhood studies. However, differences in MTO's effects across the five cities have been largely ignored. Such differences could be due to population composition (e.g., differences in the racial/ethnic distribution) or to context (e.g., differences in the economy). Using a nonparametric omnibus test and a multiply robust, semiparametric estimator for transportability, we assessed the extent to which differences in individual-level compositional characteristics that may act as effect modifiers can account for differences in MTO's effects across sites. We examined MTO's effects on marijuana use, behavioral problems, major depressive disorder, and generalized anxiety disorder among black and Latino adolescent males, where housing voucher receipt was harmful for health in some sites but beneficial in others. Comparing point estimates, differences in composition partially explained site differences in MTO effects on marijuana use and beh...Continue Reading

References

Jun 1, 1996·Journal of Pediatric Psychology·S McDermottD F Wuori
Jul 26, 2002·Social Science & Medicine·Sally MacintyreSteven Cummins
Oct 4, 2007·Statistical Applications in Genetics and Molecular Biology·Mark J van der LaanAlan E Hubbard
Mar 3, 2009·Journal of the American Academy of Child and Adolescent Psychiatry·Ronald C KesslerKathleen R Merikangas
Apr 4, 2009·Clinical Trials : Journal of the Society for Clinical Trials·Constantine Frangakis
Jun 16, 2010·American Journal of Epidemiology·Stephen R Cole, Elizabeth A Stuart
Oct 30, 2010·Statistical Methods in Medical Research·Maya L PetersenMark J van der Laan
Apr 30, 2014·Journal of Applied Statistics·Stephanie SappJohn Canny
Apr 1, 2001·Journal of the Royal Statistical Society. Series A, (Statistics in Society)·Elizabeth A StuartPhilip J Leaf
Sep 6, 2014·American Journal of Epidemiology·Kara E RudolphElizabeth A Stuart
Oct 1, 2008·American Sociological Review·Barrett A LeeDavid O'Sullivan
Feb 11, 2015·Journal of the Royal Statistical Society. Series B, Statistical Methodology·Elizabeth L OgburnJames M Robins
Oct 22, 2015·American Journal of Epidemiology·Daniel Westreich, Jessie K Edwards
Jan 30, 2018·Journal of the Royal Statistical Society. Series B, Statistical Methodology·Kara E Rudolph, Mark J van der Laan

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Citations

Mar 13, 2019·Circulation. Cardiovascular Quality and Outcomes·Seth A BerkowitzSanjay Basu
Nov 26, 2019·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Megha L MehrotraElvin H Geng
Apr 12, 2020·Biometrics·Kara E RudolphMark J van der Laan
Mar 17, 2019·American Journal of Epidemiology·Magdalena Cerdá, Katherine M Keyes
Dec 4, 2019·JAMA : the Journal of the American Medical Association·Craig Evan PollackBradley Herring
Feb 16, 2021·Current Epidemiology Reports·Catherine R LeskoJessie K Edwards
Feb 23, 2021·American Journal of Epidemiology·Megha L MehrotraDavid V Glidden
Aug 5, 2021·Epidemiology·Andrew EdmondsAdaora A Adimora
Nov 19, 2021·Epidemiologic Reviews·Magdalena CerdáKatherine M Keyes

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