Compounds Identification in Semen Cuscutae by Ultra-High-Performance Liquid Chromatography (UPLCs) Coupled to Electrospray Ionization Mass Spectrometry

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
Ying ZhangXiangri Li

Abstract

Semen Cuscutae is commonly used in traditional Chinese medicine and contains a series of compounds such as flavonoids, chlorogenic acids and lignans. In this study, we identified different kinds of compositions by ultra-high-performance liquid chromatography (UPLC) coupled to electrospray ionization mass spectrometry (MS). A total of 45 compounds were observed, including 20 chlorogenic acids, 23 flavonoids and 2 lignans. 23 of them are reported for the first time including 6-O-caffeoyl-β-glucose, 3-O-(4'-O-Caffeoylglucosyl) quinic acid, etc. Their structures were established by retention behavior, extensive analyses of their MS spectra and further determined by comparison of their MS data with those reported in the literature. As chlorogenic acids and flavonoids are phenolic compounds that are predominant in Semen Cuscutae, in conclusion, phenolic compounds are the major constituents of Semen Cuscutae.

References

May 2, 2003·Journal of Agricultural and Food Chemistry·Michael N CliffordNikolai Kuhnert
Feb 5, 2004·Journal of Mass Spectrometry : JMS·Filip Cuyckens, Magda Claeys
May 12, 2005·Journal of Agricultural and Food Chemistry·Michael N CliffordNikolai Kuhnert
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Sep 10, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Song YangXiangri Li

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Citations

Sep 21, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Marcello LocatelliAndrei Mocan
Jul 22, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jiao LiuYanxu Chang
Dec 31, 2019·Evidence-based Complementary and Alternative Medicine : ECAM·Jiayuan ShenJun He
Mar 20, 2021·Phytochemical Analysis : PCA·César Augusto Gonçalves DantasJosean Fechine Tavares
Jun 9, 2021·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Xiaoli WangChuanshan Jin

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