Comprehensive characterization of natural organic matter by MALDI- and ESI-Fourier transform ion cyclotron resonance mass spectrometry

Analytica Chimica Acta
Dong CaoYuehui Kang

Abstract

Natural organic matter (NOM) is a complex and non-uniform mixture of organic compounds which plays an important role in environmental processes. Due to the complexity, it is challenging to obtain fully detailed structural information about NOM. Although Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) has been demonstrated to be a powerful tool for providing molecular information about NOM, multiple ionization methods are needed for comprehensive characterization of NOM at the molecular level considering the ionizing selectivity of different ionization methods. This paper reports the first use of matrix assisted laser desorption/ionization (MALDI) method coupled with FT-ICR-MS for molecular characterization of NOM within a mass range of 200-800 Da. The mass spectral data obtained by MALDI were systematically compared with data generated by electrospray ionization (ESI). It showed that complementary molecular information about NOM which could not be detected by ESI, were provided by MALDI. More unsaturated and aromatic constituents of NOM with lower O/C ratio (O/C ratio<0.5) were preferentially ionized in MALDI negative mode, whereas more polar constituents of NOM with higher O/C ratio were preferentially ...Continue Reading

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Citations

Oct 19, 2016·Journal of the American Society for Mass Spectrometry·Will KewDušan Uhrín
Jan 8, 2017·Rapid Communications in Mass Spectrometry : RCM·William KewDušan Uhrín
Jan 18, 2018·Journal of the American Society for Mass Spectrometry·Jasmine HertzogFrédéric Aubriet
Oct 27, 2017·Analytical Chemistry·Eunji ChoSunghwan Kim
Mar 24, 2017·Analytical Chemistry·John W T BlackburnDušan Uhrín
Feb 23, 2020·Environmental Science & Technology·Juliana R LaszakovitsAllison A MacKay

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