Abstract
The aim of this study was to observe the symptom improvement and clinical benefit in elderly patients with advanced non-small cell lung cancer (NSCLC) stratified on the basis of CGA findings after treatment with a combination of traditional Chinese medicine and Western medicine. Twenty-four elderly advanced NSCLC patients with a mean age of 73.0 ± 5.3 (65-83) years were categorized into three stratifications according to CGA results, namely function independent, mildly function impaired, and function dependent. They received standardized therapy, individualized therapy, and best supportive care, respectively. The patients receiving standardized therapy and individualized therapy were randomized into two groups, with or without traditional Chinese medicine for symptom control, while for all the patients receiving best supportive care, traditional Chinese medicine was administered. Nine non-elderly NSCLC patients (<65 years old) were enrolled as control and treated in accordance with NCCN NSCLC treatment guidelines. EORTC QLQ-C30 core scale, LC13 scale, and MDASI-TCM scale were used to assess relevant symptoms before and after treatment. After treatment for 3 weeks, it was shown by QLQ-C30+LC13 scales, for function-dependent pati...Continue Reading
References
Jul 12, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M ExtermannL Balducci
Jan 22, 2004·Critical Reviews in Oncology/hematology·Cheryl Chia-Hui ChenRuth McCorkle
Jul 1, 2004·CA: a Cancer Journal for Clinicians·Arti Hurria, Mark G Kris
Jun 29, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Arati V RaoHarvey Jay Cohen
Aug 9, 2005·Critical Reviews in Oncology/hematology·Martine ExtermannUNKNOWN Task Force on CGA of the International Society of Geriatric Oncology
Dec 17, 2009·Critical Reviews in Oncology/hematology·Siri R KristjanssonTorgeir B Wyller
Jul 9, 2010·CA: a Cancer Journal for Clinicians·Ahmedin JemalElizabeth Ward
Jul 21, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sumanta Kumar Pal, Arti Hurria
Oct 5, 2010·Critical Reviews in Oncology/hematology·Pascal ChaïbiJean-Philippe Spano
Feb 8, 2011·Maturitas·Ari VanderWaldeKaren L Reckamp
Jun 29, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Philippe CailletElena Paillaud
Aug 24, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ravindran KanesvaranDonald Poon
May 19, 2012·World Journal of Surgical Oncology·Ruth M ParksKwok-Leung Cheung
Nov 17, 2012·The American Journal of the Medical Sciences·Marco RuizJohn Estrada
Dec 19, 2012·Archives of Gerontology and Geriatrics·Kwang-Il KimCheol-Ho Kim
Nov 2, 2013·Oncology Letters·Faruk TasSenem Karabulut
Nov 6, 2013·Journal of Traditional Chinese Medicine = Chung I Tsa Chih Ying Wen Pan·Guoqiang LinHaihe Jiang
Citations
Jun 29, 2016·Clinical Lung Cancer·Karlijn J G SchulkesLeontine J R van Elden
Oct 26, 2018·Integrative Cancer Therapies·Jun NiCatherine L Granger
Jan 11, 2020·BMC Palliative Care·Anna OrianiNancy J Preston
Nov 16, 2016·ESMO Open·Christine Marosi, Marcus Köller
Nov 2, 2019·Journal of Ethnopharmacology·Rui LiQi Zhao
Oct 17, 2020·Chinese Medical Journal·Xiao-Lin SuQiu-Hong Wang
Apr 16, 2021·Journal of the National Comprehensive Cancer Network : JNCCN·Kah Poh LohMelisa L Wong
Sep 22, 2020·Complementary Therapies in Medicine·Ming-Hsien YehTe-Mao Li