Comprehensive geriatric assessment and traditional Chinese medicine intervention benefit symptom control in elderly patients with advanced non-small cell lung cancer

Medical Oncology
Dong XuePingping Li

Abstract

The aim of this study was to observe the symptom improvement and clinical benefit in elderly patients with advanced non-small cell lung cancer (NSCLC) stratified on the basis of CGA findings after treatment with a combination of traditional Chinese medicine and Western medicine. Twenty-four elderly advanced NSCLC patients with a mean age of 73.0 ± 5.3 (65-83) years were categorized into three stratifications according to CGA results, namely function independent, mildly function impaired, and function dependent. They received standardized therapy, individualized therapy, and best supportive care, respectively. The patients receiving standardized therapy and individualized therapy were randomized into two groups, with or without traditional Chinese medicine for symptom control, while for all the patients receiving best supportive care, traditional Chinese medicine was administered. Nine non-elderly NSCLC patients (<65 years old) were enrolled as control and treated in accordance with NCCN NSCLC treatment guidelines. EORTC QLQ-C30 core scale, LC13 scale, and MDASI-TCM scale were used to assess relevant symptoms before and after treatment. After treatment for 3 weeks, it was shown by QLQ-C30+LC13 scales, for function-dependent pati...Continue Reading

References

Jul 12, 2002·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M ExtermannL Balducci
Jan 22, 2004·Critical Reviews in Oncology/hematology·Cheryl Chia-Hui ChenRuth McCorkle
Jul 1, 2004·CA: a Cancer Journal for Clinicians·Arti Hurria, Mark G Kris
Jun 29, 2005·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Arati V RaoHarvey Jay Cohen
Aug 9, 2005·Critical Reviews in Oncology/hematology·Martine ExtermannUNKNOWN Task Force on CGA of the International Society of Geriatric Oncology
Jul 9, 2010·CA: a Cancer Journal for Clinicians·Ahmedin JemalElizabeth Ward
Jul 21, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Sumanta Kumar Pal, Arti Hurria
Feb 8, 2011·Maturitas·Ari VanderWaldeKaren L Reckamp
Jun 29, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Philippe CailletElena Paillaud
Aug 24, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ravindran KanesvaranDonald Poon
May 19, 2012·World Journal of Surgical Oncology·Ruth M ParksKwok-Leung Cheung
Nov 2, 2013·Oncology Letters·Faruk TasSenem Karabulut
Nov 6, 2013·Journal of Traditional Chinese Medicine = Chung I Tsa Chih Ying Wen Pan·Guoqiang LinHaihe Jiang

❮ Previous
Next ❯

Citations

Jun 29, 2016·Clinical Lung Cancer·Karlijn J G SchulkesLeontine J R van Elden
Nov 16, 2016·ESMO Open·Christine Marosi, Marcus Köller
Apr 16, 2021·Journal of the National Comprehensive Cancer Network : JNCCN·Kah Poh LohMelisa L Wong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.