Comprehensive meta-analysis reveals association between multiple imprinting disorders and conception by assisted reproductive technology

Journal of Assisted Reproduction and Genetics
Victoria K CortessisKimberly D Siegmund

Abstract

To determine whether a history of conception by assisted reproductive technology (ART) is associated with occurrence of one or more imprinting disorders of either maternal or paternal origin. We implemented a systematic review of scholarly literature followed by comprehensive meta-analysis to quantitatively synthesize data from reports relating to use of ART to occurrence of any imprinting disorder of humans, including Beckwith-Wiedemann (BWS), Angelman (AS), Prader-Willi (PWS), and Silver-Russell (SRS) syndromes, as well as transient neonatal diabetes mellitus (TNDB) and sporadic retinoblasoma (RB). The systematic review identified 13 reports presenting unique data from 23 studies that related conception following ART to occurrence of imprinting disorders. Multiple studies of four disorder were identified, for which meta-analysis yielded the following summary estimates of associations with a history of ART: AS, summary odds ratio (sOR) = 4.7 (95% confidence interval (CI) 2.6-8.5, 4 studies); BWS, sOR = 5.8 (95% CI 3.1-11.1, 8 studies); PWS, sOR = 2.2 (95% CI 1.6-3.0, 6 studies); SRS, sOR = 11.3 (95% CI 4.5-28.5, 3 studies). Only one study reported on each of TNDB and RB. Published data reveal positive associations between hist...Continue Reading

References

Jul 1, 1992·American Journal of Medical Genetics·D F CallenE A Haan
Jan 1, 1991·Mechanisms of Ageing and Development·V M Reading, R A Weale
Jul 1, 1993·Journal of Assisted Reproduction and Genetics·N KültürsayG Yüce
Apr 1, 1996·Prenatal Diagnosis·S L ChristianD H Ledbetter
Oct 16, 1996·American Journal of Medical Genetics·J MitchellW P Robinson
Oct 2, 1998·Human Reproduction·J TesarikC Mendoza
Apr 16, 1999·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·R J SnijdersK H Nicolaides
Jul 17, 1999·International Journal of Technology Assessment in Health Care·S E Buitendijk
Mar 17, 2001·Nature Reviews. Genetics·W Reik, J Walter
Dec 4, 2001·Fertility and Sterility·E M SartorelliJ M de Pina-Neto
Mar 8, 2002·The New England Journal of Medicine·Laura A SchieveLynne S Wilcox
May 23, 2002·American Journal of Human Genetics·Gerald F CoxBernhard Horsthemke
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Nov 20, 2002·American Journal of Human Genetics·Michael R DeBaunAndrew P Feinberg
Jan 15, 2003·Journal of Medical Genetics·E R MaherM M Hawkins
Apr 30, 2004·Statistics in Medicine·Michael J SweetingPaul C Lambert
Jan 25, 2005·Human Reproduction·Ojvind LidegaardAnders Nyboe Andersen
Jan 29, 2005·Birth Defects Research. Part A, Clinical and Molecular Teratology·Bengt KällénPetra Otterblad Olausson
Jun 1, 2006·Current Opinion in Obstetrics & Gynecology·Øjvind LidegaardAnders Nyboe Andersen
Jan 27, 2007·Developmental Medicine and Child Neurology·I Sanchez-AlbisuaI Krägeloh-Mann
Jun 26, 2007·Human Reproduction·Marianne E DoornbosRaoul C M Hennekam
Oct 9, 2007·Human Reproduction·Sarah BowdinWilliam Reardon
Dec 25, 2007·Journal of Medical Genetics·S Abu-AmeroG E Moore
Jul 16, 2008·American Journal of Medical Genetics. Part a·Bernhard Horsthemke, Joseph Wagstaff
Oct 23, 2008·European Journal of Human Genetics : EJHG·Deniz KanberBernhard Horsthemke
Dec 25, 2008·Birth Defects Research. Part A, Clinical and Molecular Teratology·Louise Wilkins-HaugCarol B Benson
Feb 10, 2009·Fertility and Sterility·Somjate ManipalviratnJames Segars
Jun 2, 2009·Fertility and Sterility·Georgina M ChambersG David Adamson
Mar 9, 2010·Reproductive Biomedicine Online·Jennifer L KingBradley J Van Voorhis
Dec 14, 2011·Asian Journal of Andrology·Zofnat Wiener-MegnaziMartha Dirnfeld

❮ Previous
Next ❯

Citations

Jul 23, 2019·Epigenetics : Official Journal of the DNA Methylation Society·Sneha ManiMonica Mainigi
Oct 22, 2019·Human Reproduction Update·Maria ArgyrakiAlexandros Lambropoulos
Nov 22, 2019·Developmental Medicine and Child Neurology·Deniz Aygun, Hans T Bjornsson
Apr 1, 2020·Genes·Flavia CerratoAndrea Riccio
Apr 24, 2020·Human Reproduction·Min YeRi-Cheng Chian
May 13, 2020·Human Reproduction·A A HenningsenØ Lidegaard
Mar 8, 2019·Nature Reviews. Endocrinology·Frédéric BrioudeIrene Netchine
Jan 17, 2019·Nature Reviews. Genetics·David MonkAndrea Riccio
Feb 9, 2019·Clinical Epigenetics·Hiromitsu HattoriTakahiro Arima
Nov 17, 2020·Frontiers in Pediatrics·Joshua Manor, Seema R Lalani
Nov 11, 2020·International Journal of Molecular Sciences·Emily A HarrisWipawee Winuthayanon
Dec 15, 2020·Clinical Epigenetics·Patricia FauqueFabienne Pessione
Apr 3, 2021·Frontiers in Cell and Developmental Biology·Haibo ZhuQi Zhou
Apr 15, 2021·Reproductive Medicine and Biology·Yukiko Katagiri, Yuko Tamaki
Jul 29, 2021·Molecular Human Reproduction·Samantha L Wilson, Mary Wallingford

❮ Previous
Next ❯

Related Concepts

Related Feeds

Beckwith-Wiedemann syndrome

Beckwith-Wiedemann syndrome is an imprinting disorder characterized by overgrowth, congenital malformations and predisposition to tumors. Discover the latest research on Beckwith-Wiedemann Syndrome here.

Related Papers

Fertility and Sterility
Somjate ManipalviratnJames Segars
Seminars in Reproductive Medicine
Ali Eroglu, Lawrence C Layman
Epigenomics
Derek Hk Lim, Eamonn R Maher
© 2021 Meta ULC. All rights reserved