Comprehensive review of sentinel lymphadenectomy in breast cancer

Clinical Breast Cancer
P R Kelemen

Abstract

Sentinel lymph node dissection (SLND) is a minimally invasive technique to stage axillary lymph nodes in breast cancer. The complications associated with SLND are minimal, especially when compared to routine axillary lymph node dissection (ALND), and it can be performed with an overall identification rate of greater than 90% and a false-negative rate less than 5%. Despite this, SLND is not ready to replace routine axillary dissection, since we have no long-term results for these patients. What the clinical recurrence rates will be in women who undergo SLND only and how that will translate into survival rates has yet to be discovered. SLND is also a difficult technique to perform, as documented in the early SLND studies. It is imperative that each individual surgeon perform a series of cases in which SLND is combined with immediate ALND, so that identification rates and false-negative rates can be determined. Once a track record of successfully performed SLND has been established, SLND can be solely used for node-negative women. It is strongly recommended that all surgeons join one of the National Cancer Institute (NCI)-sponsored clinical trials for SLND in early breast cancer, so that many of these questions concerning SLND can...Continue Reading

References

Sep 1, 1977·International Journal of Radiation Oncology, Biology, Physics·C D Haagensen
Mar 1, 1992·The British Journal of Surgery·A L HoeI Taylor
Apr 1, 1992·Archives of Surgery·D L MortonA J Cochran
May 1, 1991·Journal of Computer Assisted Tomography·D E MarchL Needleman
Dec 1, 1986·International Journal of Radiation Oncology, Biology, Physics·R D PeznerK H Luk
Dec 1, 1969·Annals of Surgery·H R Butcher
Dec 1, 1969·Annals of Surgery·C D Haagensen, E Cooley
Nov 1, 1969·Cancer·B FisherI D Bross
Jan 1, 1971·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·P BucalossiC Cantù
Mar 1, 1980·The British Journal of Surgery·A O LanglandsT Hamilton
Dec 1, 1982·The British Journal of Surgery·J P Lythgoe, M K Palmer
Jan 1, 1981·Breast Cancer Research and Treatment·J Hayward
Sep 1, 1993·Human Pathology·I A NasserM L Silverman
Sep 1, 1995·Annals of Surgery·A E GiulianoD L Krasne
Sep 1, 1994·Annals of Surgery·A E GiulianoD L Morton
Apr 1, 1993·The British Journal of Surgery·P J HainsworthR C Bennett
Dec 11, 1996·JAMA : the Journal of the American Medical Association·J J AlbertiniD S Reintgen
Mar 4, 1998·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R M RoumenL M Geuskens
Mar 24, 1998·Journal of the American College of Surgeons·P J BorgsteinS Meijer
Apr 17, 1998·Journal of the American College of Surgeons·B J O'HeaH S Cody
Aug 6, 1998·The British Journal of Surgery·M M FlettT G Cooke
Oct 1, 1998·The New England Journal of Medicine·D KragP Beitsch
Nov 4, 1998·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·B A KapteijnB B Kroon
Nov 17, 1998·American Journal of Surgery·H SniderD Oleske
Feb 2, 1999·American Journal of Surgery·F E NwariakuG N Peters
Feb 2, 1999·American Journal of Surgery·I T RubioV S Klimberg
Mar 2, 1999·Journal of the National Cancer Institute·U VeronesiD Scarpa
Mar 5, 1999·Journal of the American College of Surgeons·S M FeldmanP Klein
Mar 17, 1999·The American Journal of Surgical Pathology·R R TurnerA E Giuliano
May 11, 1999·Annals of Surgery·H S CodyP I Borgen

❮ Previous
Next ❯

Citations

Jan 5, 2002·Cancer Biotherapy & Radiopharmaceuticals·R J BoldB N Fahy
Mar 28, 2002·Cancer Biotherapy & Radiopharmaceuticals·Richard J Bold
Dec 10, 2003·Seminars in Oncology·Ann H PartridgeHarold J Burstein
Nov 18, 2005·The Breast : Official Journal of the European Society of Mastology·Jeffery PeppercornEric P Winer
Oct 16, 2003·Journal of the National Cancer Institute·Stephen B EdgeJane C Weeks
Jul 1, 2005·Pflügers Archiv : European journal of physiology·David M Cohen
Jul 31, 2004·Cancer Control : Journal of the Moffitt Cancer Center·Thomas N ChirikosStephen L Luther

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
A Y de KanterT Wiggers
© 2022 Meta ULC. All rights reserved