Compressed-sensing accelerated 4D flow MRI of cerebrospinal fluid dynamics.

Fluids and Barriers of the CNS
Elena JaegerAlexander C Bunck

Abstract

4D flow magnetic resonance imaging (MRI) of CSF can make an important contribution to the understanding of hydrodynamic changes in various neurological diseases but remains limited in clinical application due to long acquisition times. The aim of this study was to evaluate the accuracy of compressed SENSE accelerated MRI measurements of the spinal CSF flow. In 20 healthy subjects 4D flow MRI of the CSF in the cervical spine was acquired using compressed sensitivity encoding [CSE, a combination of compressed sensing and parallel imaging (SENSE) provided by the manufacturer] with acceleration factors between 4 and 10. A conventional scan using SENSE was used as reference. Extracted parameters were peak velocity, absolute net flow, forward flow and backward flow. Bland-Altman analysis was performed to determine the scan-rescan reproducibility and the agreement between SENSE and compressed SENSE. Additionally, a time accumulated flow error was calculated. In one additional subject flow of the spinal canal at the level of the entire spinal cord was assessed. Averaged acquisition times were 10:21 min (SENSE), 9:31 min (CSE4), 6:25 min (CSE6), 4:53 min (CSE8) and 3:51 min (CSE10). Acquisition of the CSF flow surrounding the entire spi...Continue Reading

References

Oct 3, 1999·Journal of Neurosurgery·J D HeissE H Oldfield
Jul 7, 2007·Journal of Biopharmaceutical Statistics·J Martin Bland, Douglas G Altman
Jun 11, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ricardo OtazoDaniel K Sodickson
Mar 26, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Bernd JungMichael Markl
Oct 6, 2011·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Marcus CarlssonHåkan Arheden
Dec 6, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Hung-Yu LinOrlando P Simonetti
Aug 14, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Verena KnoblochSebastian Kozerke
Oct 16, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Yongjun KwakReza Nezafat
Oct 18, 2012·Physics in Medicine and Biology·F LiuA Kangarlu
Jan 1, 2014·Fluids and Barriers of the CNS·Shinya YamadaJames Gordon McComb
Jun 20, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Daniel GieseSebastian Kozerke
Feb 13, 2015·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Steffi Dreha-KulaczewskiJens Frahm
Sep 25, 2015·The British Journal of Radiology·Oren N JaspanMichael L Lipton
Apr 12, 2016·Seminars in Ultrasound, CT, and MR·Erin J Kelly, Shinya Yamada
Dec 17, 2016·Journal of Magnetic Resonance Imaging : JMRI·Li FengHersh Chandarana
Sep 25, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Corey A BaronDwight G Nishimura
Feb 22, 2018·The Neuroradiology Journal·Erika Kristina LindstrømKent-Andre Mardal
May 10, 2018·Journal of Magnetic Resonance Imaging : JMRI·Jolanda M SpijkermanJaco J M Zwanenburg
Feb 26, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Liliana E MaNing Jin
Mar 10, 2019·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Julia J SchubertFederico E Turkheimer
Aug 21, 2019·Frontiers in Aging Neuroscience·Thomas SartorettiSabine Sartoretti-Schefer
Oct 23, 2019·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Elisabeth NeuhausDaniel Giese

❮ Previous
Next ❯

Software Mentioned

Matlab
R
GTFlow
PCMRI
studio
REML

Related Concepts

Related Feeds

Blood Brain Barrier Chips

The blood brain barrier (BBB) is comprised of endothelial cells that regulate the influx and outflux of plasma concentrations. Lab-on-a-chip devices allow scientists to model diseases and mechanisms such as the passage of therapeutic antibodies across the BBB. Discover the latest research on BBB chips here.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Blood Brain Barrier

The blood brain barrier is a border that separates blood from cerebrospinal fluid. Discover the latest search on this highly selective semipermeable membrane here.