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Computational design of small transcription activating RNAs for versatile and dynamic gene regulation

Nature Communications

Oct 21, 2017

James ChappellJulius B Lucks

Abstract

A longstanding goal of synthetic biology has been the programmable control of cellular functions. Central to this is the creation of versatile regulatory toolsets that allow for programmable control of gene expression. Of the many regulatory molecules available, RNA regulators offer the...read more

Mentioned in this Paper

Alkalescens-Dispar Group
Metabolic Networks and Pathways
CRISPR-Cas Systems
Transcription, Genetic
Gene Expression
Steroidogenic acute regulatory protein
Cellular Reprogramming
Metabolic Pathway
Addition to Lower Extremity, Patten Bottom
Terminator Regions, Genetic
47
6
148
Paper Details
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Computational design of small transcription activating RNAs for versatile and dynamic gene regulation

Nature Communications

Oct 21, 2017

James ChappellJulius B Lucks

PMID: 29051490

DOI: 10.1038/s41467-017-01082-6

Abstract

A longstanding goal of synthetic biology has been the programmable control of cellular functions. Central to this is the creation of versatile regulatory toolsets that allow for programmable control of gene expression. Of the many regulatory molecules available, RNA regulators offer the...read more

Mentioned in this Paper

Alkalescens-Dispar Group
Metabolic Networks and Pathways
CRISPR-Cas Systems
Transcription, Genetic
Gene Expression
Steroidogenic acute regulatory protein
Cellular Reprogramming
Metabolic Pathway
Addition to Lower Extremity, Patten Bottom
Terminator Regions, Genetic
47
6
148

Feeds With Similar Papers

CRISPR for Genome Editing

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.

Gene Regulation, Differentiation & Reprogramming (Keystone)

This feed focuses on alterations of gene regulation during cell differentation and reprogramming processes. Here is the latest research on gene regulation in differentiation and reprogramming processes.

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Current Opinion in Chemical Biology

A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future(opens in new tab)

Current Opinion in Chemical BiologyJune 22, 2015
James ChappellJulius B Lucks
Paper Details
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    References currently unavailable

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