PMID: 8950657Nov 1, 1996Paper

Computational evaluation of intraventricular pressure gradients based on a fluid-structure approach

Journal of Biomechanical Engineering
A Redaelli, Franco M Montevecchi

Abstract

The dynamics of intraventricular blood flow, i.e. its rapid evolution, implies the rise of intraventricular pressure gradients (IPGs) characteristic of the inertia-driven events as experimentally observed by Pasipoularides (1987, 1990) and by Falsetti et al. (1986). The IPG time course is determined by the wall contraction which, in turn, depends on the load applied, namely the intraventricular pressure which is the sum of the aortic pressure (i.e., the systemic net response) and the IPG. Hence the IPGs account, at least in part, for the wall movement. These considerations suggest the necessity of a comprehensive analysis of the ventricular mechanics involving both ventricular wall mechanics and intraventricular fluid dynamics as each domain determines the boundary conditions of the other. This paper presents a computational approach to ventricular ejection mechanics based on a fluid-structure interaction calculation for the evaluation of the IPG time course. An axisymmetric model of the left ventricle is utilized. The intraventricular fluid is assumed to be Newtonian. The ventricle wall is thin and is composed of two sets of counter-rotating fibres which behave according to the modified version of Wong's sarcomere model propos...Continue Reading

References

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Citations

Mar 4, 2000·Medical & Biological Engineering & Computing·P VerdonckE Dick
Mar 18, 2005·Biomechanics and Modeling in Mechanobiology·Francesco Migliavacca, Gabriele Dubini
Jun 17, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·F MaisanoO Alfieri
Dec 4, 2003·Medical Engineering & Physics·Alberto RedaelliFranco Maria Montevecchi
Sep 8, 2010·Journal of Biomechanical Engineering·Umberto MorbiducciAlberto Redaelli
Nov 26, 2013·Biomedical Engineering Online·Hamidreza Ghasemi BahrasemanNaser Fatourayee
May 11, 2010·International Journal for Numerical Methods in Engineering·Daniel R EinsteinMark B Ratcliffe
Jan 11, 2002·Journal of Biomechanical Engineering·A RedaelliO Alfieri
Feb 24, 2001·Journal of Biomechanical Engineering·J A VierendeelsP R Verdonck
Sep 30, 2005·Journal of Magnetic Resonance Imaging : JMRI·Richard G WiseChristopher L-H Huang
Jul 25, 2000·Journal of Applied Physiology·A RedaelliF M Montevecchi
Sep 13, 2005·Computer Methods in Biomechanics and Biomedical Engineering·Jaroslav Mackerle

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