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Computational methods for transcriptome annotation and quantification using RNA-seq

Nature Methods

Jun 1, 2011

Manuel G GarberCole Trapnell

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Abstract

High-throughput RNA sequencing (RNA-seq) promises a comprehensive picture of the transcriptome, allowing for the complete annotation and quantification of all genes and their isoforms across samples. Realizing this promise requires increasingly complex computational methods. These compu...read more

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References
    • References56
    • Citations307
    • References56
    • Citations307
  • Computational methods for transcriptome annotation and quantification using RNA-seq

    Nature Methods

    Jun 1, 2011

    Manuel G GarberCole Trapnell

    PMID: 21623353

    DOI: 10.1038/nmeth.1613

    Abstract

    High-throughput RNA sequencing (RNA-seq) promises a comprehensive picture of the transcriptome, allowing for the complete annotation and quantification of all genes and their isoforms across samples. Realizing this promise requires increasingly complex computational methods. These compu...read more

    14
    2
    3484
    Paper Details
    References
    • References56
    • Citations307
    • References56
    • Citations307
  • Get paper from

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