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Computational methods for transcriptome annotation and quantification using RNA-seq

Nature Methods

May 31, 2011

Manuel GarberCole Trapnell

Abstract

High-throughput RNA sequencing (RNA-seq) promises a comprehensive picture of the transcriptome, allowing for the complete annotation and quantification of all genes and their isoforms across samples. Realizing this promise requires increasingly complex computational methods. These compu...read more

Mentioned in this Paper

Sequence Determinations, RNA
Genomics
High-Throughput Nucleotide Sequencing
High-Throughput RNA Sequencing
Transcriptome
MRNA Differential Display
Computational Molecular Biology
Determination, Sequence Homology
14
2
3569
Paper Details
References
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  • Citations344
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  • References77
  • Citations344
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Computational methods for transcriptome annotation and quantification using RNA-seq

Nature Methods

May 31, 2011

Manuel GarberCole Trapnell

PMID: 21623353

DOI: 10.1038/nmeth.1613

Abstract

High-throughput RNA sequencing (RNA-seq) promises a comprehensive picture of the transcriptome, allowing for the complete annotation and quantification of all genes and their isoforms across samples. Realizing this promise requires increasingly complex computational methods. These compu...read more

Mentioned in this Paper

Sequence Determinations, RNA
Genomics
High-Throughput Nucleotide Sequencing
High-Throughput RNA Sequencing
Transcriptome
MRNA Differential Display
Computational Molecular Biology
Determination, Sequence Homology
14
2
3569

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Structural Biology: Biophysics

Structural Biology: Biophysics describes the study of structural biology using various biophysical techiniques such as imaging, computational modeling, etc. Discover the latest research on structrual biology here.

CZI Human Cell Atlas Seed Network

The aim of the Human Cell Atlas (HCA) is to build reference maps of all human cells in order to enhance our understanding of health and disease. The Seed Networks for the HCA project aims to bring together collaborators with different areas of expertise in order to facilitate the development of the HCA. Find the latest research from members of the HCA Seed Networks here.

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Science China. Life Sciences

Overview of available methods for diverse RNA-Seq data analyses

Science China. Life SciencesJanuary 10, 2012
Geng ChenTieliu Shi
Paper Details
References
  • References77
  • Citations344
12345...
  • References77
  • Citations344
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