PMID: 9637625Jun 24, 1998Paper

Computed imaging-assisted stereotactic brain biopsy: a risk analysis of 225 consecutive cases

Surgical Neurology
P D SawinJ C Torner

Abstract

Treatment strategies for intracranial mass lesions are most effective when based upon histopathological diagnoses. Image-guided stereotaxy has provided the means to sample tissue from small or deeply seated intraparenchymal lesions with a relatively high degree of safety and accuracy. Although procedural complications are infrequent, devastating neurological sequelae may result from hemorrhage or direct trauma. This study was undertaken to identify factors that may confer an increased risk of morbidity from stereotactic brain biopsy. Two hundred twenty-five consecutive computer-assisted stereotactic brain biopsy procedures were reviewed. Patient age averaged 47.4 years (range, 3-84 years); gender ratio was approximately 2:1 (male:female). Pre-existing medical conditions were identified in nearly half of the cohort. 61.3% of biopsied lesions were lobar; the remainder (38.7%) were "deep-seated" (thalamus, basal ganglia, pineal, hypothalamus, cerebellum, brainstem). Glial tumors accounted for the majority (44.4%) of biopsied lesions; metastases (12.9%) and lymphoma (11.6%) were also relatively common. Demographical, anatomical, surgical, and histological data were compiled and putative risk factors for morbidity identified. These ...Continue Reading

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Citations

Jul 28, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ali MeshkiniAmir Hamdi
Jan 6, 2000·Journal of the Neurological Sciences·D KarussisO Abramsky
Sep 25, 2003·Surgical Neurology·A J Gonçalves-FerreiraJ Pimentel
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Jan 7, 2005·Neurologia Medico-chirurgica·Christopher NimskyRudolf Fahlbusch
Apr 16, 2013·Journal of Neurosurgery. Pediatrics·Shlomi ConstantiniShizuo Oi
Apr 15, 2003·Journal of Neurosurgery·Leonardo FrighettoDennis Chute
Apr 2, 2008·Journal of Neurosurgery·Mel Boulton, Mark Bernstein
Oct 10, 2013·Acta neurochirurgica·Hiroshi OobaMinoru Fujiki
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Aug 17, 2002·Neurosurgery·Ratan D Bhardwaj, Mark Bernstein

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