Computed Tomographic Angiography of the Pancreas in Cats with Chronic Diabetes Mellitus Compared to Normal Cats

Journal of Veterinary Internal Medicine
Scott SecrestAndrew Bugbee

Abstract

Diabetes mellitus (DM) is a common endocrinopathy in cats. No known diagnostic test or patient characteristic at the time of diagnosis can predict likely disease course, unlike in people in whom computed tomographic angiography (CTA) is used. No published data exist regarding the CTA appearance of the pancreas in cats with DM, and thus, it is unknown what if any CTA variables should be further assessed for associations with pancreatic endocrine function. A significant difference in pancreatic attenuation, volume, and size will be identified between normal cats and those with chronic DM on CTA. Ten healthy control cats and 15 cats with naturally occurring DM present for >12 months. Prospective cross-sectional study comparing pancreatic attenuation, enhancement pattern, size, volume, pancreatic volume-to-body weight ratio (V:BW), pancreatic arterial: portal phase ratio (A:P), time-to-arterial enhancement, and time-to-peak portal enhancement on CTA between sedated healthy control cats and those with chronic DM. The pancreas in cats with chronic DM was significantly larger, had higher volume, higher V:BW, and shorter time-to-peak portal enhancement on CTA when compared to normal cats. Peak portal enhancement time, pancreatic size, ...Continue Reading

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Citations

May 21, 2019·Anatomia, histologia, embryologia·Damri Darawiroj, Nan Choisunirachon
Feb 16, 2021·Journal of Veterinary Internal Medicine·Marnin A FormanKatja Steiger

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Methods Mentioned

BETA
pancreatectomy
sedation
biopsy

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