Computed tomography-based attenuation correction in neurological positron emission tomography: evaluation of the effect of the X-ray tube voltage on quantitative analysis

Nuclear Medicine Communications
Mohammad Reza Ay, H Zaidi

Abstract

The advent of dual-modality positron emission tomography/computed tomography (PET/CT) imaging has revolutionized the practice of clinical oncology by improving lesion localization and facilitating treatment planning for radiation therapy. In addition, the use of CT images for CT-based attenuation correction (CTAC) allows the overall scanning time to be decreased and a noise-free attenuation map (micromap) to be created. The most common procedure requires a piecewise linear calibration curve acquired under standard imaging conditions to convert the patient's CT image from low effective CT energy into an attenuation map at 511 keV. To evaluate the effect of the tube voltage on the accuracy of CTAC. As different tube voltages are employed in current PET/CT scanning protocols, depending on the size of the patient and the region under study, the impact of using a single calibration curve on the accuracy of CTAC for images acquired at different tube voltages was investigated through quantitative analysis of the created micromaps, generated attenuation correction factors and reconstructed neurological PET data using anthropomorphic experimental phantom and clinical studies. For CT images acquired at 80 and 140 kVp, average relative di...Continue Reading

References

Nov 4, 1998·Medical Physics·P E KinahanD Sashin
May 11, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Ehab KamelAlfred Buck
Jul 12, 2002·European Journal of Nuclear Medicine and Molecular Imaging·C BurgerG K Von Schulthess
Aug 22, 2003·Seminars in Nuclear Medicine·Paul E KinahanThomas Beyer
Aug 22, 2003·Seminars in Nuclear Medicine·David W TownsendTodd M Blodgett
Oct 10, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Tung-Hsin WuTieh-Chi Chu
Oct 24, 2003·European Journal of Nuclear Medicine and Molecular Imaging·Habib ZaidiDaniel O Slosman
Mar 1, 2005·NeuroImage·Marie-Louise Montandon, Habib Zaidi
Apr 29, 2005·Radiology·Barton F BranstetterCarolyn C Meltzer
Apr 20, 2006·European Journal of Nuclear Medicine and Molecular Imaging·Mohammad Reza Ay, Habib Zaidi

❮ Previous
Next ❯

Citations

Apr 18, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Alireza AhmadianHabib Zaidi
Apr 7, 2011·European Journal of Nuclear Medicine and Molecular Imaging·Livia Tossici-BoltAndrea Varrone
Apr 14, 2010·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Mohammad R AyHabib Zaidi
Feb 24, 2012·Annals of Nuclear Medicine·Akio NagakiNorikazu Matsutomo
Jul 1, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Rob S B Beanlands, George Youssef
Apr 1, 2007·PET Clinics·Sandip BasuAbass Alavi
Apr 1, 2007·PET Clinics·Andrew J Reader, Habib Zaidi
Jun 5, 2016·European Journal of Nuclear Medicine and Molecular Imaging·Ali Afshar-OromiehUwe Haberkorn
Jun 28, 2016·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Sanaz KavianiMohammad Reza Ay
Nov 3, 2015·Seminars in Nuclear Medicine·Eric SalmonRoland Hustinx
Jun 6, 2009·Seminars in Nuclear Medicine·Andreas BockischTorsten Kuwert
May 6, 2016·Medical Physics·Chiara Dolores SoffientiniGiuseppe Baselli
Nov 23, 2006·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Marie-Louise Montandon, Habib Zaidi
Jul 9, 2013·Nature Medicine·Simon Walker-SamuelXavier Golay
Apr 10, 2012·Medical Physics·B TeimourianH Zaidi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.