Computed tomography (CT) has been used to quantitate acute myocardial infarct size in isolated, arrested canine hearts. Acute myocardial infarcts were produced in 20 hearts by either left anterior descending (13 dogs) or circumflex coronary artery ligation (seven dogs). Each animal was given iodinated contrast media intravenously immediately before sacrifice 24--72 hours postinfarction. All infarcts greater than 1 g and one of three infarcts 0.5 g or less were detected by CT imaging. Infarct volume determined by CT correlated with gross infarct weight (r=0.83). CT imaging, however, consistently underestimated infarct volume; underestimation was largest in a group of patchy, predominantly subendocardial infarcts. As adequate equipment and techniques for in vivo studies are developed, CT imaging of the heart may become important in clinical evaluation of myocardial infarction.
Pathophysiology of technetium-99m stannous pyrophosphate and thallium-201 scintigraphy of acute anterior myocardial infarcts in dogs.
Quantification of infarction in cross sections of canine myocardium in vivo with positron emission transaxial tomography and 11C-palmitate
Inability of methylprednisolone sodium succinate to decrease infarct size or preserve enzyme activity measured 24 hours after coronary occlusion in the dog.
Detection of edema associated with myocardial ischemia by computerized tomography in isolated, arrested canine hearts.
Precordial S-T segment elevation mapping: an atraumatic method for assessing alterations in the extent of myocardial ischemic injury. The effects of pharmacologic and hemodynamic interventions
Quantitative assessment of the extent of myocardial infarction in the conscious dog by means of analysis of serial changes in serum creatine phosphokinase activity
Effects of transient coronary ischemia and reperfusion on myocardial edema formation and in vitro magnetic relaxation times
Myocardial infarct size determined by computed transmission tomography in canine infarcts of various ages and in the presence of coronary reperfusion
Insights into the assessment of myocardial perfusion offered by different cardiac imaging modalities
Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar
Impact of tube current in the quantitative assessment of acute reperfused myocardial infarction with 64-slice delayed-enhancement CT: a porcine model
Impact of contrast material volume on quantitative assessment of reperfused acute myocardial infarction using delayed-enhancement 64-slice CT: experience in a porcine model.
In vivo evaluation of myocardial infarction by computed tomography: an experiment with electrocardiographic gating
Prognostic significance of regional wall motion abnormality in patients with prior myocardial infarction: a prospective correlative study of two-dimensional echocardiography and angiography
Imaging of acute myocardial infarction in man with contrast-enhanced computed transmission tomography
ECG synchronized computed tomography in clinical evaluation of total and regional cardiac motion: comparison of postmyocardial infarction to normal hearts by rapid sequential imaging
Measurement of infarct size in acute canine myocardial infarction by single-photon emission computed tomography with technetium-99m pyrophosphate
Assessment of drug intervention on the ischemic myocardium: serial imaging and measurement with computerized tomography
In vivo assessment by computed tomography of the natural progression of infarct size, left ventricular muscle mass and function after acute myocardial infarction in the dog
Multislice computed tomography and magnetic resonance imaging for the assessment of reperfused acute myocardial infarction
Prospective electrocardiogram-gated delayed enhanced multidetector computed tomography accurately quantifies infarct size and reduces radiation exposure
State of the Art: Imaging for Myocardial Viability: A Scientific Statement From the American Heart Association.
Assessment of myocardial delayed enhancement with cardiac computed tomography in cardiomyopathies: a prospective comparison with delayed enhancement cardiac magnetic resonance imaging
Discover the latest cardiology research in this collection of the top cardiology journals.