Computed tomography-guided catheter drainage with urokinase and ozone in management of empyema

World Journal of Radiology
Bing LiXiao-Xue Xu

Abstract

To retrospectively compare the outcomes of catheter drainage, urokinase and ozone in management of empyema. Retrospective study included 209 patients (111 males and 98 females; age range 19 to 72 years) who were diagnosed with empyema. The patients were divided into 3 groups based on the therapy instituted: catheter drainage only (group I); catheter drainage and urokinase (group II); catheter drainage, urokinase and ozone (group III). Drainage was considered successful if empyema was resolved with closure of cavity, clinical symptoms were resolved, and need for any further surgical procedure was avoided. Success rate, length of stay (LOS), need for further surgery and hospital costs were compared between the three groups using the Kruskall-Wallis nonparametric test, with P < 0.05 considered significant. Of the 209 patients with empyema, all catheters were placed successfully under CT guidance. Sixty-three patients were treated with catheters alone (group I), 64 with catheters and urokinase (group II), and 82 with catheters, urokinase and ozone (group III). Group I, group II and group III had success rates of 62%, 83% and 95% respectively (P < 0.05). Group I and group II had statistically longer LOS (P < 0.05) and higher hospita...Continue Reading

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Citations

Aug 9, 2019·The European Respiratory Journal·Tamsin N CargillNajib M Rahman
May 1, 2018·Canadian Journal of Gastroenterology & Hepatology·Bing LiHan Feng Yang

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