Computer-aided classification of lung nodules on computed tomography images via deep learning technique

OncoTargets and Therapy
Kai-Lung HuaYu-Jen Chen

Abstract

Lung cancer has a poor prognosis when not diagnosed early and unresectable lesions are present. The management of small lung nodules noted on computed tomography scan is controversial due to uncertain tumor characteristics. A conventional computer-aided diagnosis (CAD) scheme requires several image processing and pattern recognition steps to accomplish a quantitative tumor differentiation result. In such an ad hoc image analysis pipeline, every step depends heavily on the performance of the previous step. Accordingly, tuning of classification performance in a conventional CAD scheme is very complicated and arduous. Deep learning techniques, on the other hand, have the intrinsic advantage of an automatic exploitation feature and tuning of performance in a seamless fashion. In this study, we attempted to simplify the image analysis pipeline of conventional CAD with deep learning techniques. Specifically, we introduced models of a deep belief network and a convolutional neural network in the context of nodule classification in computed tomography images. Two baseline methods with feature computing steps were implemented for comparison. The experimental results suggest that deep learning methods could achieve better discriminative ...Continue Reading

Citations

Oct 22, 2016·Cancer Letters·Jean-Emmanuel BibaultAnita Burgun
Jul 31, 2016·Briefings in Bioinformatics·Seonwoo MinSungroh Yoon
Jun 18, 2017·International Journal of Computer Assisted Radiology and Surgery·Amal A FaragAly A Farag
Feb 24, 2018·International Journal of Computer Assisted Radiology and Surgery·Xinzhuo ZhaoWei Qian
Mar 1, 2018·Journal of Medical Imaging·Barath Narayanan NarayananTemesguen Messay Kebede
Jun 6, 2019·Physics in Medicine and Biology·Jing GongWeijun Peng
Jan 24, 2020·Physics in Medicine and Biology·Chenyang ShenXun Jia
Oct 28, 2019·Journal of Digital Imaging·Sara RanjbarLeland S Hu
May 27, 2020·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Stefania RizzoFrancesco Petrella
Jul 30, 2019·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Tomoyuki NoguchiTsuyoshi Tajima
Apr 26, 2018·Journal of Cellular Biochemistry·Yiwei CaoCaihong Guo
May 24, 2019·BioMed Research International·Guangyuan ZhengChunwu Zhou
Apr 12, 2019·Frontiers in Genetics·Binhua TangAsif Khateeb
Aug 28, 2019·Cancers·Khushboo MunirAntonello Rizzi
Oct 22, 2019·Frontiers in Oncology·Luca BoldriniMartin-Immanuel Bittner
Mar 13, 2021·Der Urologe. Ausg. A·D Bonekamp, H-P Schlemmer
Mar 29, 2021·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Mehdi AstarakiChunliang Wang
Jul 26, 2021·Medical & Biological Engineering & Computing·Chen ZhaoMenglin Wu

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Methods Mentioned

BETA
biopsy
feature extraction

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