PMID: 9650186Jul 3, 1998Paper

Computer-aided diagnosis: automatic detection of malignant masses in digitized mammograms

Medical Physics
A J MéndezJ J Vidal

Abstract

A computerized method to automatically detect malignant masses on digital mammograms based on bilateral subtraction to identify asymmetries between left and right breast images was developed. After the digitization, in order to align left and right mammograms the breast border and nipple were automatically detected. Images were corrected to avoid differences in brightness due to the recording procedure. Left and right mammograms were subtracted and a threshold was applied to obtain a binary image with the information of suspicious areas. The suspicious regions or asymmetries were delimited by a region growing algorithm. Size and eccentricity tests were used to eliminate false-positive responses and texture features were extracted from suspicious regions to reject normal tissue regions. The scheme, tested in 70 pairs of digital mammograms, achieved a true-positive rate of 71% with an average number of 0.67 false positives per image. Computerized detection was evaluated by using free-response operating characteristic analysis (FROC). An area under the AFROC (A1) of 0.667 was obtained. Our results show that the scheme may be helpful to the radiologists by serving as a second reader in mammographic screening. The low number of fals...Continue Reading

References

Sep 1, 1992·Radiology·R E BirdB C Yankaskas
Jun 1, 1991·Computers and Biomedical Research, an International Journal·T K Lau, W F Bischof
Sep 1, 1989·Radiology·J M Eskridge
Nov 1, 1989·Radiology·E A Sickles
Jul 1, 1982·CA: a Cancer Journal for Clinicians·L H Baker
Jan 1, 1995·Physics in Medicine and Biology·P G TahocesJ J Vidal
May 1, 1994·Radiology·C J Vyborny
May 1, 1994·Radiology·W P KegelmeyerM L Nipper
Feb 1, 1994·Medical Physics·R M NishikawaR A Schmidt
May 1, 1996·Computer Methods and Programs in Biomedicine·A J MéndezJ J Vidal
Jan 1, 1990·IEEE Transactions on Medical Imaging·D BrzakovicP Brzakovic
Jan 1, 1989·IEEE Transactions on Medical Imaging·S M LaiW F Biscof

❮ Previous
Next ❯

Citations

Dec 8, 2000·Journal of Digital Imaging·R L ArensonR G Gould
Aug 26, 2006·Medical & Biological Engineering & Computing·Yujun GuoSwamy Laxminarayan
Jun 12, 2003·Computer Methods and Programs in Biomedicine·Javier QuilesJuan J Vidal
Feb 6, 2004·Computer Methods and Programs in Biomedicine·P MayoJ M Campayo
Feb 4, 1999·Journal of Women's Health
Feb 21, 2003·Annals of the New York Academy of Sciences·Antônio C Roque, Túlio C S S André
Oct 7, 2006·Medical Physics·Bin ZhengDavid Gur
Jul 21, 2009·Medical Physics·Matthias Elter, Alexander Horsch
Jul 15, 2005·Medical Physics·Shalini Gupta, Mia K Markey
Apr 17, 2007·Academic Radiology·Wei QianEdward Eikman
Jan 1, 2009·IEEE Reviews in Biomedical Engineering·Metin N GurcanB Yener
Apr 29, 2014·IEEE Transactions on Medical Imaging·Umamahesh SrinivasBhushan Jayarao
Apr 19, 2006·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·María J LadoPablo G Tahoces
Jan 29, 2002·IEEE Transactions on Medical Imaging·Y HatanakaT Iwase
Oct 14, 2003·IEEE Transactions on Medical Imaging·Mónica PenedoJuan J Vidal
Mar 25, 2005·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Sameer Singh, Keir Bovis
Apr 20, 2006·Computers in Biology and Medicine·Celia VarelaJuan J Vidal
Aug 5, 2015·BioMed Research International·José Celaya-PadillaJosé Tamez-Peña
Apr 4, 2015·Journal of Pathology Informatics·Hojjat Seyed MousaviArvind U K Rao
Dec 30, 2014·Computers in Biology and Medicine·Yanfeng LiLin Cao
Mar 13, 2001·Medical Physics·G M te Brake, N Karssemeijer
Jun 27, 2015·Investigative Radiology·Dennis MackinLaurence Court
Nov 4, 2017·The Analyst·Marcus T Cicerone, Charles H Camp
Jan 25, 2020·Current Medical Imaging Reviews·Afrooz ArzehgarFatemeh Varshoei
Aug 26, 2010·Physics in Medicine and Biology·Matthias ElterThomas Wittenberg
Jul 14, 2010·SIAM Journal on Imaging Sciences·Eugene Demidenko
Feb 12, 2002·Physics in Medicine and Biology·John DamilakisNicholas Gourtsoyiannis
Mar 30, 2021·Medical Image Analysis·Yuhang LiuGuangming Lu
Jun 15, 2021·Neural Processing Letters·Koyel Datta GuptaChing-Hsien Hsu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.