Computer-aided diagnosis based on enhancement of degraded fundus photographs

Acta Ophthalmologica
Kai JinDahong Qian

Abstract

Retinal imaging is an important and effective tool for detecting retinal diseases. However, degraded images caused by the aberrations of the eye can disguise lesions, so that a diseased eye can be mistakenly diagnosed as normal. In this work, we propose a new image enhancement method to improve the quality of degraded images. A new method is used to enhance degraded-quality fundus images. In this method, the image is converted from the input RGB colour space to LAB colour space and then each normalized component is enhanced using contrast-limited adaptive histogram equalization. Human visual system (HVS)-based fundus image quality assessment, combined with diagnosis by experts, is used to evaluate the enhancement. The study included 191 degraded-quality fundus photographs of 143 subjects with optic media opacity. Objective quality assessment of image enhancement (range: 0-1) indicated that our method improved colour retinal image quality from an average of 0.0773 (variance 0.0801) to an average of 0.3973 (variance 0.0756). Following enhancement, area under curves (AUC) were 0.996 for the glaucoma classifier, 0.989 for the diabetic retinopathy (DR) classifier, 0.975 for the age-related macular degeneration (AMD) classifier and 0...Continue Reading

References

Aug 1, 1987·Ophthalmology·E Peli, B Schwartz
Nov 14, 1997·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·J Liang, D R Williams
Sep 19, 2000·Radiographics : a Review Publication of the Radiological Society of North America, Inc·E D PisanoS M Pizer
Apr 28, 2005·Medical Image Analysis·Marco ForacchiaAlfredo Ruggeri
Sep 13, 2005·Progress in Retinal and Eye Research·Niall PattonIan J Constable
Jun 7, 2007·Zeitschrift für medizinische Physik·Ingo Koschmieder, Lothar Müller
Jan 1, 1989·IEEE Transactions on Medical Imaging·E Peli, T Peli
Sep 9, 2008·Investigative Ophthalmology & Visual Science·Pauline H B KokFrank D Verbraak
Jun 23, 2009·Medical Image Analysis·Clara I SánchezRoberto Hornero
Sep 23, 2010·The British Journal of Ophthalmology·Alan D FlemingJohn A Olson
Jun 15, 2011·Investigative Ophthalmology & Visual Science·Carla AgurtoPeter Soliz
Sep 29, 2011·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Rui BernardesConceição Lobo
Nov 25, 2011·Journal of Biomedical Optics·Andrés G MarrugoMaría S Millán
Mar 1, 2012·European Radiology·K A MilesUNKNOWN Experimental Cancer Medicine Centre Imaging Network Group
Apr 11, 2013·Investigative Ophthalmology & Visual Science·Mark J J P van GrinsvenClara I Sánchez
Jan 30, 2014·Journal of Biomedical Optics·Andrés G MarrugoFilip Sroubek
Dec 17, 2015·IEEE Transactions on Medical Imaging·Shaoze WangDahong Qian
Apr 15, 2016·IEEE Transactions on Medical Imaging·Tim JermanZiga Spiclin
Oct 1, 2016·International Journal of Biomedical Imaging·Peishan DaiMin Fan

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Citations

Jan 4, 2020·Medical & Biological Engineering & Computing·Lvchen Cao, Huiqi Li
Oct 17, 2020·Scientific Reports·Mohammad Ali SaghiriNader Sheibani

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