Computer-aided diagnosis of colorectal polyps using linked color imaging colonoscopy to predict histology

Scientific Reports
Min MinYan Liu

Abstract

We developed a computer-aided diagnosis (CAD) system based on linked color imaging (LCI) images to predict the histological results of polyps by analyzing the colors of the lesions. A total of 139 images of adenomatous polyps and 69 images of non-adenomatous polyps obtained from our hospital were collected and used to train the CAD system. A test set of LCI images, including both adenomatous and non-adenomatous polyps, was prospectively collected from patients who underwent colonoscopies between Oct and Dec 2017; this test set was used to assess the diagnostic abilities of the CAD system compared to those of human endoscopists (two experts and two novices). The accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of this novel CAD system for the training set were 87.0%, 87.1%, 87.0%, 93.1%, and 76.9%, respectively. The test set included 115 adenomatous polyps and 66 non-adenomatous polyps that were prospectively collected. The CAD system identified adenomatous or non-adenomatous polyps in the test set with an accuracy of 78.4%, a sensitivity of 83.3%, a specificity of 70.1%, a PPV of 82.6%, and an NPV of 71.2%. The accuracy of the CAD system was comparable to that of the expert...Continue Reading

Associated Clinical Trials

Feb 11, 2021·Elisa Gravito-Soares, Elisa Gravito-Soares

References

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Citations

Apr 25, 2020·Gastroenterology Research and Practice·Xue Sun, Li Zhao
Sep 29, 2020·World Journal of Gastroenterology : WJG·Ke-Wei Wang, Ming Dong
Apr 8, 2020·Clinical Endoscopy·Alexander P AbadirJason B Samarasena
Feb 27, 2020·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Majid A Almadi, Khek Yu Ho
Oct 21, 2020·Journal of Clinical Medicine·Hemant GoyalSumant Inamdar
Oct 9, 2019·Gastroenterology·Catherine Le BerreLaurent Peyrin-Biroulet
May 1, 2021·Current Oncology·Athanasia MitsalaAlexandra K Tsaroucha
May 29, 2021·Scientific Data·Pia H SmedsrudPål Halvorsen
Jun 23, 2021·Digestive Diseases and Sciences·Yutaka OkagawaYutaka Saito
Jun 29, 2021·Therapeutic Advances in Gastrointestinal Endoscopy·Alexander R RobertsonAnastasios Koulaouzidis

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Methods Mentioned

BETA
biopsy

Clinical Trials Mentioned

NCT03359343

Software Mentioned

SPSS
Statistical Package for the Social Sciences

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