Computer-Aided Diagnosis of Pancreas Serous Cystic Neoplasms: A Radiomics Method on Preoperative MDCT Images

Technology in Cancer Research & Treatment
Ran WeiJianqing Zhu

Abstract

Our aim was to propose a preoperative computer-aided diagnosis scheme to differentiate pancreatic serous cystic neoplasms from other pancreatic cystic neoplasms, providing supportive opinions for clinicians and avoiding overtreatment. In this retrospective study, 260 patients with pancreatic cystic neoplasm were included. Each patient underwent a multidetector row computed tomography scan and pancreatic resection. In all, 200 patients constituted a cross-validation cohort, and 60 patients formed an independent validation cohort. Demographic information, clinical information, and multidetector row computed tomography images were obtained from Picture Archiving and Communication Systems. The peripheral margin of each neoplasm was manually outlined by experienced radiologists. A radiomics system containing 24 guideline-based features and 385 radiomics high-throughput features was designed. After the feature extraction, least absolute shrinkage selection operator regression was used to select the most important features. A support vector machine classifier with 5-fold cross-validation was applied to build the diagnostic model. The independent validation cohort was used to validate the performance. Only 31 of 102 serous cystic neopl...Continue Reading

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Citations

Jul 28, 2020·Diagnostics·Jorge D MachicadoSomashekar G Krishna
Oct 22, 2020·Japanese Journal of Radiology·Marion BartoliPhilippe Soyer
Nov 6, 2020·European Radiology·Bassam M AbunahelMaxim S Petrov
Nov 5, 2019·Biochimica Et Biophysica Acta. Reviews on Cancer·Joseph CarmichealSurinder K Batra
Feb 8, 2021·Japanese Journal of Radiology·Maxime BaratPhilippe Soyer
Oct 17, 2020·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Myrte GorrisJeanin E van Hooft
Mar 2, 2021·Therapeutic Advances in Gastrointestinal Endoscopy·Hemant GoyalBenjamin Tharian
Sep 30, 2020·Current Problems in Diagnostic Radiology·Linda C ChuElliot K Fishman
Jul 3, 2021·Mathematical Biosciences and Engineering : MBE·Chengkang LiYuanyuan Wang
Jul 23, 2021·Abdominal Radiology·Mayur VirarkarPriya Bhosale
Aug 14, 2021·La Radiologia medica·Grigory KarmazanovskyAmiran Revishvili

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Methods Mentioned

BETA
surgical resection
feature extraction

Software Mentioned

LASSO
Matlab
Picture Archiving and Communication

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