Abstract
Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) is able to detect breast cancer with high sensitivity. Furthermore, this method provides functional information on tissue composition and vascularization. This study aims to identify the potential of DCE-MRI to predict distant metastasis in breast cancer patients using computer assisted interpretation of dynamic enhancement data. For this purpose, 59 consecutive patients with newly diagnosed invasive breast cancer received pretherapeutic DCE-MRI at 1.5 Tesla according to international recommendations. In all patients, follow up interval and occurrence of distant metastasis was documented. For DCE-MRI analysis dedicated software was used (Brevis, Siemens Healthcare, Erlangen, Germany). It allows semiautomatic identification of the most suspect curve in a lesion analyzed. Enhancement parameters assessed were "Initial Enhancement", "Washout", "Peak-Enhancement", and "Time to Peak Enhancement". Cox proportional hazards regression (CPHR) was used to analyze the effect of these parameters on the probability of metachronous distant metastasis. Median follow up period was 52.0 months. 6 patients developed distant metastases between 11 and 35 months after breast cancer diagn...Continue Reading
References
May 25, 1994·JAMA : the Journal of the American Medical Association
Jan 1, 1997·CA: a Cancer Journal for Clinicians·W L Donegan
Aug 22, 1997·International Journal of Cancer. Journal International Du Cancer·A ObermairR Zeillinger
Oct 3, 1999·Journal of Magnetic Resonance Imaging : JMRI·M V KnoppG van Kaick
Mar 1, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·David L Buckley
Oct 13, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James L KhatcheressianUNKNOWN American Society of Clinical Oncology
Apr 4, 2007·American Journal of Obstetrics and Gynecology·Florian SchuetzChristof Sohn
Apr 5, 2008·European Radiology·R M MannC Boetes
Apr 17, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Paul L NguyenJay R Harris
Jun 21, 2008·Radiology·Ka-Loh LiNola M Hylton
Jun 24, 2008·European Journal of Radiology·Martin D PicklesLindsay W Turnbull
Oct 23, 2008·Topics in Magnetic Resonance Imaging : TMRI·Wendy DeMartini, Constance Lehman
May 29, 2009·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael J Thun
Aug 10, 2011·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·P SanpaoloD Genovesi
Citations
Jul 27, 2015·European Journal of Radiology·Maciej A MazurowskiKaren S Johnson
May 6, 2015·European Journal of Radiology·Athina C TsiliMaria I Argyropoulou
Apr 13, 2018·PloS One·Sang Yu NamJeong Eon Lee
Jan 3, 2019·AJR. American Journal of Roentgenology·Marina CodariRubina Manuela Trimboli
Dec 5, 2013·Acta Oncologica·Joachim BöttcherFlorian J Engelken
Jan 31, 2020·PloS One·Stephan EllmannTobias Bäuerle
Feb 13, 2016·Medicine·Shy-Chyi ChinKyunghyun Sung
Mar 1, 2020·Scientific Reports·Matthias DietzelPascal A T Baltzer
Sep 30, 2020·Aging·Wenjuan MaChao Zhang
Feb 4, 2021·RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin·Matthias DietzelPascal Andreas Thomas Baltzer
Jan 11, 2021·European Journal of Radiology·Pascal A T Baltzer
Oct 1, 2021·The British Journal of Radiology·Valentine MberuAndrew Evans