Computer-assisted extraction of intracranial aneurysms on 3D rotational angiograms for computational fluid dynamics modeling

Medical Physics
Herng-Hua ChangWoei-Chyn Chu


Three-dimensional rotational angiography (3DRA) is an evolving imaging procedure from traditional digital subtraction angiography and is gaining much interest for detecting intracranial aneurysms. Computational fluid dynamics (CFD) modeling plays an important role in understanding the biomechanical properties and in facilitating the prediction of aneurysm rupture. A successful computational study relies on an accurate description of the vascular geometry that is obtained from volumetric images. The authors propose a new aneurysm segmentation algorithm to facilitate the study of CFD. This software combines a region-growing segmentation method with the 3D extension of a deformable contour based on a charged fluid model. A charged fluid model essentially consists of a set of charged elements that are governed by the nature of electrostatics. The approach requires no prior knowledge of anatomic structures and automatically segments the vasculature after the end-user selects a vessel section in a plane image. Experimental results on 15 cases indicate that aneurysm structures were effectively segmented and in good agreement with manual delineation outcomes. In comparison with the existing methods, the algorithm provided a much higher...Continue Reading


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Related Concepts

Mycotic Aneurysm, Intracranial
In Silico
Models, Anatomic
Radiographic Image Interpretation, Computer-Assisted
Imaging, Three-Dimensional, Computer Assisted
Angiography, Digital Subtraction

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