Abstract
To investigate the efficacy of the PAPNET Testing System and its ability to detect significant areas on clinically important false negative gynecologic smears. Sixty-two gynecologic smears that had been obtained from women studied in a previous case-control investigation, completed in 1987, and had originally been interpreted as negative were rescreened by two independent, blind cytotechnologist-cytopathologist teams. Twenty-nine of these "negative" smears were from 19 women who had been subsequently diagnosed with invasive squamous cell carcinoma and had self-reported a history of only negative gynecologic smears. Thirty-three smears were from 33 control women who did not develop cervical cancer. One team, at the University of Southern California (USC), manually rescreened the smears as part of the original study. The other team, at the University of California at Los Angeles (UCLA), recently used the PAPNET Testing System to rescreen the same smears. This computer-assisted system utilizes neural network technology to recognize and select potentially abnormal cell scenes on a conventionally prepared gynecologic smear. The PAPNET-selected scenes are displayed for review by trained cytologists, who ultimately diagnose the smear....Continue Reading
Citations
Jul 1, 1996·Cancer·M R Kok, M E Boon
Feb 12, 1998·Cancer·A A Renshaw
Nov 4, 1998·Cancer·M E ShermanA T Lorincz
Feb 6, 1998·Diagnostic Cytopathology·S MasoodC W Bedrossian
Aug 14, 1998·Diagnostic Cytopathology·H Mitchell, G Medley
Oct 24, 1998·Diagnostic Cytopathology·D GhidoniA Bondi
Jun 8, 2001·Cancer·M R KokL P Kok
May 23, 2002·The Annals of Thoracic Surgery·Hugo EstevaMercedes Esteva
May 29, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S P Michalas
Sep 26, 2000·Journal of Clinical Pathology·L RozendaalC J Meijer
Jan 11, 2007·CytoJournal·Pranab Dey
Dec 13, 2007·Thoracic Surgery Clinics·Hugo EstevaRicardo O Rodríguez
Aug 28, 2009·Cancer·Fadi BrimoManon Auger
Oct 16, 2010·Diagnostic Cytopathology·Heather WilgenbuschAndrew A Renshaw
Jan 24, 2006·Artificial Intelligence in Medicine·Reeti TandonJeffrey A Kaye
Nov 23, 2005·Cancer·Amina DjemliManon Auger
Dec 10, 1999·Cytopathology : Official Journal of the British Society for Clinical Cytology·J A HalfordE J Ditchmen
Dec 10, 1999·Cytopathology : Official Journal of the British Society for Clinical Cytology·M R KokM E Boon
Jun 25, 1998·Cytopathology : Official Journal of the British Society for Clinical Cytology·J P O'SullivanC A Waddell
Oct 6, 1997·Cytopathology : Official Journal of the British Society for Clinical Cytology·H DoornewaardJ G van den Tweel
Apr 13, 1999·Obstetrical & Gynecological Survey·O Abulafia, D M Sherer