PMID: 6975560Dec 1, 1981Paper

Computer-enhanced thallium scintigrams in asymptomatic men with abnormal exercise tests

The American Journal of Cardiology
G S UhlJ R Hickman

Abstract

The use of treadmill testing in asymptomatic patients and those with an atypical chest pain syndrome is increasing, yet the proportion of false positive stress electrocardiograms increases as the prevalence of disease decreases. To determine the diagnostic accuracy of computer-enhanced thallium perfusion scintigraphy in this subgroup of patients, multigated thallium scans were obtained after peak exercise and 3 or 4 hours after exercise and the raw images enhanced by a computer before interpretations were made. The patient group consisted of 191 asymptomatic U.S. Air force aircrewmen who had an abnormal exercise electrocardiogram. Of these, 135 had normal coronary angiographic findings, 15 had subcritical coronary stenosis (less than 50 percent diameter narrowing) and 41 had significant coronary artery disease. Use of computer enhancement resulted in only four false positive and two false negative scintigrams. The small subgroup with subcritical coronary disease had equivocal results on thallium scintigraphy, 10 men having abnormal scans and 5 showing no defects. The clinical significance of such subcritical disease in unclear, but it can be detected with thallium scintigraphy. Thallium scintigrams that have been enhanced by re...Continue Reading

References

Aug 2, 1979·The New England Journal of Medicine·S E Epstein
Jan 11, 1976·Progress in Cardiovascular Diseases·V F FroelicherM C Lancaster

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Citations

Aug 30, 2000·Diabetes Research and Clinical Practice·I CastellsA Sanmartí
Mar 1, 1983·Journal of the American College of Cardiology·G S Uhl, V Froelicher
Apr 1, 1986·British Heart Journal·P R WalkerJ R Rees
Dec 1, 1985·Disease-a-month : DM·H C Sox
Apr 1, 1987·Current Problems in Cardiology·G J Dehmer
Apr 1, 1987·Seminars in Nuclear Medicine·A Rozanski, D S Berman
Apr 1, 1988·The American Journal of Medicine·R DetranoV F Froelicher
May 1, 1989·Clinical Cardiology·J LindsayS A Goldstein
May 15, 1991·The American Journal of Cardiology·A LangerP W Armstrong
Dec 1, 1982·Circulation·K L Gould
Oct 1, 1994·Stroke; a Journal of Cerebral Circulation·S UrbinatiG Pinelli
Jan 1, 1987·Circulation·D S BermanS B Knoebel
Feb 13, 2003·Circulation·Roger S BlumenthalLewis C Becker

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